Triterpenoid saponins from the genus Camellia: structures, biological activities, and molecular simulation for structure-activity relationship

被引：50
|
作者：
Cui, Chuanjian [1 ]
Zong, Jianfa [1 ]
Sun, Yue [1 ]
Zhang, Liang [1 ]
Ho, Chi-Tang [2 ]
Wan, Xiaochun [1 ]
Hou, Ruyan [1 ]
机构：
[1] Anhui Agr Univ, Sch Tea & Food Sci & Technol, Int Joint Lab Tea Chem & Hlth Effects, State Key Lab Tea Plant Biol & Utilizat, Hefei 230036, Anhui, Peoples R China
[2] Rutgers State Univ, Food Sci Dept, 65 Dudley Rd, New Brunswick, NJ 08901 USA
来源：
FOOD & FUNCTION | 2018年 / 9卷 / 06期
关键词：
TEA SEED SAPONIN; CHAKASAPONINS I-III; CELL-CYCLE ARREST; FLOWER BUDS; OLEANANE-TYPE; BIOACTIVE SAPONINS; DEFATTED SEEDS; GASTROINTESTINAL TRANSIT; ANTIALLERGIC ACTIVITY; QUANTITATIVE-ANALYSIS;
D O I：
10.1039/c8fo00755a
中图分类号：
Q5 [生物化学]; Q7 [分子生物学];
学科分类号：
071010 ; 081704 ;
摘要：
This review summarizes the isolation, chemical identification, and biochemical activities of Camellia triterpenoid saponins, updating a previous review and encompassing all new studies through September 2017. Further, molecular simulations of the interaction between several known cytotoxic oleiferasaponin monomers and Interleukin-6 are discussed, demonstrating that molecular modeling is a convenient method to obtain structure-activity information.
引用
收藏
页码：3069 / 3091
页数：23
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