Neuroimaging technique using time-resolved diffuse optical tomography and inhomogeneity localization algorithm

The method for obtaining functional images of human brain or another soft biological tissue and its phantoms based on the time-resolved diffuse optical tomography is described. The developed method is based on the principles of near infrared spectroscopy, in particular on the increased probing depth in optical transparency window and the differences in the absorption spectra of oxygenated and deoxygenated blood. The key feature of the approach is fast search and dynamical visualization of the most oxygenated sections of an investigated object using improved mapping algorithm for localization of absorbing inhomogeneities. Hydrodynamic phantoms with pulsatile blood flow in the thickness of biological tissues were used for validation of the described method.