Coincidence of renal artery stenosis and coronary artery stenosis

Aims The aim of this study was to investigate the prevalence of renal artery stenosis in patients with severe coronary artery disease or stenosis of the left main coronary artery. Materials and methods This cross-sectional study was performed on 264 patients with a history of severe hypertension who were candidates for coronary artery angiography in Yazd Afshar Hospital. During coronary angiography, renal angiography was performed on all of the patients. At the same time, we investigated the renal artery stenosis and its association with a history of diabetes mellitus, high body mass index (BMI), hyperlipidemia, and other cardiovascular risk factors. Renal artery stenosis was defined based on luminal narrowing: mild (50%), moderate (75%), and severe (75%) decrease in luminal diameter. Collected data were analyzed by SPSS software (version 18.0). Results Among 264 patients, 54.92% were males and 45.08 % were females with the average age of 58.0 +/- 8.6. 83.71% of the patients had coronary artery disease and included 52.94% hyperglycemic, 63.39% diabetic, and 29.86% smokers. Prevalence of the renal artery stenosis (equal to or more than 50%) was 38.25% in all patients, including 43.56% in men and 56.44%, in women, which shows a significant difference (P=0.04). Prevalence of comorbidity of coronary artery disease and renal artery stenosis for 1-vessel, 2-vessels, and 3-vessels disease was 34%, 57.14%, and 54.17%, respectively, that showed a significant difference (P< 0.01). Conclusion Our findings showed a high prevalence (38.25%) of renal artery stenosis in hypertensive patients with coronary artery diseases. Accordingly, we suggest that simultaneous renal angiography after coronary angiography in hypertensive patients may help to find patients with renal artery stenosis and subsequently better management of these patients.