The Role of the Insula in Classical and Dissociative PTSD: A Double Case Study

被引：0

作者：

Blades, Robin ^{[1
]}

Becerra, Sergio ^{[1
]}

Jordan, Sheldon ^{[1
,2
]}

Eusebio, Branon ^{[3
]}

Heatwole, Mark ^{[3
]}

Iovine, Jessica ^{[1
]}

Mahdavi, Kennedy ^{[1
]}

Mamoun, Michael ^{[4
]}

Nicodemus, Natalie ^{[1
]}

Packham, Hannah ^{[1
]}

Spivak, Norman ^{[5
]}

Kuhn, Taylor ^{[6
]}

机构：

[1] Neurol Associates Intervent Grp, Los Angeles, CA 90403 USA

[2] Univ Calif Los Angeles, Dept Neurol, Los Angeles, CA 90024 USA

[3] Theramind, Santa Barbara, CA USA

[4] CNS Hlth, Los Angeles, CA USA

[5] Univ Calif Los Angeles, Dept Neurosurg, Los Angeles, CA USA

[6] Univ Calif Los Angeles, Dept Psychiat & Biobehav Sci, Los Angeles, CA 90024 USA

来源：

NEUROCASE | 2022年 / 28卷 / 02期

关键词：

Insula; amygdala; anterior cingulate; dissociative ptsd; dystonia; coping strategies; POSTTRAUMATIC-STRESS-DISORDER; FUNCTIONAL CONNECTIVITY; SUBTYPE; ANXIETY; ACTIVATION; CORTEX; NETWORKS; AMYGDALA; VOLUME; FEAR;

D O I：

10.1080/13554794.2021.1978502

中图分类号：

R74 [神经病学与精神病学];

学科分类号：

摘要：

Two service members were diagnosed with PTSD due to military trauma exposure. One presented with the classical manifestation; the other presented with the dissociative subtype. A statistical map revealed anterior localization of insula connectivity in the classical PTSD patient and posterior localization in the dissociative PTSD patient. These differences suggest that dissociative PTSD may be identified, understood, and treated as a disorder related to increased posterior insula connectivity. This double case study provides preliminary evidence for a concrete neuroanatomical discrepancy between insula function in classical and dissociative PTSD that may help explain the emergence of different coping strategies.

引用

页码：140 / 148

页数：9

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