Point mutation in FKS1 gene of Candida albicans leading to echinocandin resistance after echinocandin treatment

被引:0
|
作者
Heidrich, K. [1 ]
Krause, R. [2 ]
Hoenigl, M. [2 ]
Koelli, B. [1 ]
Buzina, W. [1 ]
机构
[1] Med Univ Graz, Inst Hyg Microbiol & Environm Med, Graz, Austria
[2] Med Univ Graz, Sect Infect Dis & Trop Med, Dept Internal Med, Graz, Austria
关键词
D O I
暂无
中图分类号
R75 [皮肤病学与性病学];
学科分类号
100206 ;
摘要
V16
引用
收藏
页码:19 / 20
页数:2
相关论文
共 50 条
  • [41] Effect of Candida glabrata FKS1 and FKS2 Mutations on Echinocandin Sensitivity and Kinetics of 1,3-β-D-Glucan Synthase: Implication for the Existing Susceptibility Breakpoint
    Garcia-Effron, Guillermo
    Lee, Samuel
    Park, Steven
    Cleary, John D.
    Perlin, David S.
    ANTIMICROBIAL AGENTS AND CHEMOTHERAPY, 2009, 53 (09) : 3690 - 3699
  • [42] Elevated Cell Wall Chitin in Candida albicans Confers Echinocandin Resistance In Vivo
    Lee, Keunsook K.
    MacCallum, Donna M.
    Jacobsen, Mette D.
    Walker, Louise A.
    Odds, Frank C.
    Gow, Neil A. R.
    Munro, Carol A.
    ANTIMICROBIAL AGENTS AND CHEMOTHERAPY, 2012, 56 (01) : 208 - 217
  • [43] Resistance to echinocandins comes at a cost The impact of FKS1 hotspot mutations on Candida albicans fitness and virulence
    Ben-Ami, Ronen
    Kontoyiannis, Dimitrios P.
    VIRULENCE, 2012, 3 (01) : 95 - 97
  • [44] Recurrent episodes of Candidemia due to Candida glabrata, Candida tropicalis and Candida albicans with acquired echinocandin resistance
    Grosset, Marine
    Desnos-Ollivier, Marie
    Godet, Cendrine
    Kauffmann-Lacroix, Catherine
    Cazenave-Roblot, France
    MEDICAL MYCOLOGY CASE REPORTS, 2016, 14 : 20 - 23
  • [45] Echinocandin Treatment of Candida albicans Biofilms Enhances Neutrophil Extracellular Trap Formation
    Hoyer, Amanda R.
    Johnson, Chad J.
    Hoyer, Matthew R.
    Kernien, John F.
    Nett, Jeniel E.
    ANTIMICROBIAL AGENTS AND CHEMOTHERAPY, 2018, 62 (09)
  • [46] Reduced Candida glabrata susceptibility secondary to an FKS1 mutation developed during Candidemia treatment
    Cleary, John D.
    Garcia-Effron, Guillermo
    Chapman, Stanley W.
    Perlin, David S.
    ANTIMICROBIAL AGENTS AND CHEMOTHERAPY, 2008, 52 (06) : 2263 - 2265
  • [47] Rapid Detection of ERG11-Associated Azole Resistance and FKS-Associated Echinocandin Resistance in Candida auris
    Hou, Xin
    Lee, Annie
    Jimenez-Ortigosa, Cristina
    Kordalewska, Milena
    Perlin, David S.
    Zhao, Yanan
    ANTIMICROBIAL AGENTS AND CHEMOTHERAPY, 2019, 63 (01)
  • [48] Anidulafungin and Micafungin MIC Breakpoints Are Superior to That of Caspofungin for Identifying FKS Mutant Candida glabrata Strains and Echinocandin Resistance
    Shields, Ryan K.
    Nguyen, M. Hong
    Press, Ellen G.
    Updike, Cassaundra L.
    Clancy, Cornelius J.
    ANTIMICROBIAL AGENTS AND CHEMOTHERAPY, 2013, 57 (12) : 6361 - 6365
  • [49] Progressive loss of echinocandin activity following prolonged use for treatment of Candida albicans oesophagitis
    Laverdière, M
    Lalonde, RG
    Baril, JG
    Sheppard, DC
    Park, S
    Perlin, DS
    JOURNAL OF ANTIMICROBIAL CHEMOTHERAPY, 2006, 57 (04) : 705 - 708
  • [50] Stepwise Development of a Homozygous S80P Substitution in Fks1p, Conferring Echinocandin Resistance in Candida tropicalis
    Jensen, Rasmus Hare
    Johansen, Helle Krogh
    Arendrup, Maiken Cavling
    ANTIMICROBIAL AGENTS AND CHEMOTHERAPY, 2013, 57 (01) : 614 - 617