A with-in host Dengue infection model with immune response

被引：56
|
作者：
Nuraini, Nuning [1 ]
Tasman, Hengki [1 ]
Soewono, Edy [1 ]
Sidarto, Kuntjoro Adji [1 ]
机构：
[1] Inst Teknol Bandung, Ind & Financial Math Grp, Fac Math & Nat Sci, Bandung 40132, Indonesia
来源：
MATHEMATICAL AND COMPUTER MODELLING | 2009年 / 49卷 / 5-6期
关键词：
With-in host model; Dengue viral infection; Basic reproduction ratio; Bifurcation diagram; DISEASE; VIREMIA; VIRUS; FEVER;
D O I：
10.1016/j.mcm.2008.06.016
中图分类号：
TP39 [计算机的应用];
学科分类号：
081203 ; 0835 ;
摘要：
A model of viral infection of monocytes population by Dengue virus is formulated here. The model can capture phenomena that dengue virus is quickly cleared in approximately 7 days after the onset of the symptoms. The model takes into account the immune response. It is shown that the quantity of free virus is decreasing when the viral invasion rate is increasing. The basic reproduction ratio of model without immune response is reduced significantly by adding the immune response. Numerical simulations indicate that the growth of immune response and the invasion rate are very crucial in identification of the intensity of infection (C) 2008 Elsevier Ltd. All rights reserved.
引用
收藏
页码：1148 / 1155
页数：8
相关论文
共 50 条
  • [21] A genomics approach to understanding host response during dengue infection
    Hibberd, Martin L.
    [J]. INFECTION GENETICS AND EVOLUTION, 2008, 8 (04) : S7 - S7
  • [22] Liver transcriptomics reveals microRNA features of the host response in a mouse model of dengue virus infection
    Zheng, Wenjiang
    Wang, Ting
    Liu, Chengxin
    Yan, Qian
    Zhan, Shaofeng
    Li, Geng
    Liu, Xiaohong
    Jiang, Yong
    [J]. COMPUTERS IN BIOLOGY AND MEDICINE, 2022, 150
  • [23] Viral infection and host immune response in diabetes
    Joshi, Garima
    Das, Anushka
    Verma, Garima
    Guchhait, Prasenjit
    [J]. IUBMB LIFE, 2024, 76 (05) : 242 - 266
  • [24] Host immune response to infection with porcine circoviruses
    Shi, Ruihan
    Hou, Lei
    Liu, Jue
    [J]. ANIMAL DISEASES, 2021, 1 (01):
  • [25] PAMPs and Host Immune Response in Cryptococcal Infection
    Sato, Ko
    Kawakami, Kazuyoshi
    [J]. MEDICAL MYCOLOGY JOURNAL, 2022, 63 (04) : 133 - 138
  • [26] Host immune response to Cryptosporidium parvum infection
    Petry, Franz
    Jakobi, Vera
    Tessema, Tesfaye S.
    [J]. EXPERIMENTAL PARASITOLOGY, 2010, 126 (03) : 304 - 309
  • [27] Targeting the host immune response to fight infection
    Baillie, J. Kenneth
    [J]. SCIENCE, 2014, 344 (6186) : 807 - 808
  • [28] Host Immune Response to Influenza A Virus Infection
    Chen, Xiaoyong
    Liu, Shasha
    Goraya, Mohsan Ullah
    Maarouf, Mohamed
    Huang, Shile
    Chen, Ji-Long
    [J]. FRONTIERS IN IMMUNOLOGY, 2018, 9
  • [29] Innate Immune Memory and the Host Response to Infection
    Sherwood, Edward R.
    Burelbach, Katherine R.
    McBride, Margaret A.
    Stothers, Cody L.
    Owen, Allison M.
    Hernandez, Antonio
    Patil, Naeem K.
    Williams, David L.
    Bohannon, Julia K.
    [J]. JOURNAL OF IMMUNOLOGY, 2022, 208 (04): : 785 - 792
  • [30] The host immune response to Clostridium difficile infection
    Solomon, Katie
    [J]. THERAPEUTIC ADVANCES IN INFECTIOUS DISEASE, 2013, 1 (01) : 19 - 35
12345