Glucocorticoid receptor antagonism overcomes resistance to BRAF inhibition in BRAFV600E-mutated metastatic melanoma

被引：0
|
作者：
Obrador, E. [1 ]
Estrela, J. M. [1 ]
Salvador, R. [1 ]
Marchio, P. [1 ]
Valles, S. L. [1 ]
Lopez-Blanch, R. [1 ]
Benlloch, M. [2 ]
Alcacer, J. [3 ]
Perez, C. L. [4 ]
Pellicer, J. A. [1 ]
机构：
[1] Univ Valencia, Physiol, Valencia 46010, Spain
[2] San Vicente Martir Catholic Univ, Hlth & Funct Valorizat, Valencia 46001, Spain
[3] Quiron Hosp, Pathol Lab, Valencia 46010, Spain
[4] Inst Basic & Preclin Sci Victoria Giron, Biochem, Havana 3102146, Cuba
来源：
EUROPEAN JOURNAL OF CANCER | 2020年 / 138卷
关键词：
D O I：
暂无
中图分类号：
R73 [肿瘤学];
学科分类号：
100214 ;
摘要：
150
引用
下载
收藏
页码：S41 / S41
页数：1
相关论文
共 50 条
  • [41] Mitochondrial dysfunction and immune suppression in BRAF V600E-mutated metastatic melanoma
    de Almeida, Natalia Pinto
    Janosi, Agnes Judit
    Hong, Runyu
    Rajeh, Ahmad
    Nogueira, Fabio
    Szadai, Leticia
    Szeitz, Beata
    Pla Parada, Indira
    Doma, Viktoria
    Woldmar, Nicole
    Guedes, Jessica
    Ujfaludi, Zsuzsanna
    Bartha, Aron
    Kim, Yonghyo
    Welinder, Charlotte
    Baldetorp, Bo
    Kemeny, Lajos Vince
    Pahi, Zoltan
    Wan, Guihong
    Nguyen, Nga
    Pankotai, Tibor
    Gyorffy, Balazs
    Pawlowski, Krzysztof
    Horvatovich, Peter
    Szasz, Attila Marcell
    Sanchez, Aniel
    Kuras, Magdalena
    Murillo, Jimmy Rodriguez
    Betancourt, Lazaro
    Domont, Gilberto B.
    Semenov, Yevgeniy R.
    Yu, Kun-Hsing
    Kwon, Ho Jeong
    Nemeth, Istvan Balazs
    Fenyo, David
    Wieslander, Elisabet
    Marko-Varga, Gyorgy
    Gil, Jeovanis
    CLINICAL AND TRANSLATIONAL MEDICINE, 2024, 14 (07):
  • [42] RICTOR/mTORC2 downregulation in BRAFV600E melanoma cells promotes resistance to BRAF/MEK inhibition
    Ponzone, Luca
    Audrito, Valentina
    Landi, Claudia
    Moiso, Enrico
    Levron, Chiara Levra
    Ferrua, Sara
    Savino, Aurora
    Vitale, Nicoletta
    Gasparrini, Massimiliano
    Avalle, Lidia
    Vantaggiato, Lorenza
    Shaba, Enxhi
    Tassone, Beatrice
    Saoncella, Stefania
    Orso, Francesca
    Viavattene, Daniele
    Marina, Eleonora
    Fiorilla, Irene
    Burrone, Giulia
    Abili, Youssef
    Altruda, Fiorella
    Bini, Luca
    Deaglio, Silvia
    Defilippi, Paola
    Menga, Alessio
    Poli, Valeria
    Porporato, Paolo Ettore
    Provero, Paolo
    Raffaelli, Nadia
    Riganti, Chiara
    Taverna, Daniela
    Cavallo, Federica
    Calautti, Enzo
    MOLECULAR CANCER, 2024, 23 (01)
  • [43] OUTCOMES UTILIZING BRAF INHIBITION MONOTHERAPY IN BRAFV600E MUTATED PEDIATRIC LOW GRADE GLIOMAS
    McThenia, Sheila
    Reddy, Kartik
    Goldman-Yassen, Adam E.
    Gray, Rachel
    Connelly, Erin
    Patteson, Brooke
    Aguilera, Dolly
    Castellino, Robert Craig
    Fangusaro, Jason Ronald
    Janss, Anna
    Mazewski, Claire
    MacDonald, Tobey
    NEURO-ONCOLOGY, 2023, 25
  • [44] BRAFV600E mutated melanoma patients may have an increased rate of metastatic brain disease when compared to wild-type BRAF melanoma
    Ung, Timothy
    Shah, Kabeer
    Lillehei, Kevin
    Robinson, William
    JOURNAL OF NEUROSURGERY, 2015, 122 (06) : A1523 - A1524
  • [45] EPIDEMIOLOGY OF BRAFV600-MUTATED METASTATIC MELANOMA IN EUROPE: A SYSTEMATIC REVIEW
    Rahhali, N.
    Chalem, Y.
    Arkoub, H.
    Chollet, J.
    Bobrowska, A.
    Drane, E.
    Uchea, C.
    Wulund, L.
    Leonard, S.
    VALUE IN HEALTH, 2017, 20 (09) : A413 - A413
  • [46] Combining BRAFV600E inhibition with modulators of the mitochondrial bioenergy metabolism to overcome drug resistance in metastatic melanoma
    Livingstone, Elisabeth
    Swann, Suzanne
    Lilla, Carmen
    Schadendorf, Dirk
    Roesch, Alexander
    EXPERIMENTAL DERMATOLOGY, 2015, 24 (09) : 709 - 710
  • [47] The Role of Autophagy in the Resistance to BRAF Inhibition in BRAF-Mutated Melanoma
    Liu, Xiao
    Wu, Jinfeng
    Qin, Haihong
    Xu, Jinhua
    TARGETED ONCOLOGY, 2018, 13 (04) : 437 - 446
  • [48] The Role of Autophagy in the Resistance to BRAF Inhibition in BRAF-Mutated Melanoma
    Xiao Liu
    Jinfeng Wu
    Haihong Qin
    Jinhua Xu
    Targeted Oncology, 2018, 13 : 437 - 446
  • [49] Reversible and adaptive resistance to BRAF(V600E) inhibition in melanoma
    Sun, Chong
    Wang, Liqin
    Huang, Sidong
    Heynen, Guus J. J. E.
    Prahallad, Anirudh
    Robert, Caroline
    Haanen, John
    Blank, Christian
    Wesseling, Jelle
    Willems, Stefan M.
    Zecchin, Davide
    Hobor, Sebastijan
    Bajpe, Prashanth K.
    Lieftink, Cor
    Mateus, Christina
    Vagner, Stephan
    Grernrum, Wipawadee
    Hofland, Ingrid
    Schlicker, Andreas
    Wessels, Lodewyk F. A.
    Beijersbergen, Roderick L.
    Bardelli, Alberto
    Di Nicolantonio, Federica
    Eggermont, Alexander M. M.
    Bernards, Rene
    NATURE, 2014, 508 (7494) : 118 - +
  • [50] Reversible and adaptive resistance to BRAF(V600E) inhibition in melanoma
    Chong Sun
    Liqin Wang
    Sidong Huang
    Guus J. J. E. Heynen
    Anirudh Prahallad
    Caroline Robert
    John Haanen
    Christian Blank
    Jelle Wesseling
    Stefan M. Willems
    Davide Zecchin
    Sebastijan Hobor
    Prashanth K. Bajpe
    Cor Lieftink
    Christina Mateus
    Stephan Vagner
    Wipawadee Grernrum
    Ingrid Hofland
    Andreas Schlicker
    Lodewyk F. A. Wessels
    Roderick L. Beijersbergen
    Alberto Bardelli
    Federica Di Nicolantonio
    Alexander M. M. Eggermont
    Rene Bernards
    Nature, 2014, 508 : 118 - 122
12345