The Chicken or the Egg: MicroRNA-Mediated Regulation of mRNA Translation or mRNA Stability

被引：23
|
作者：
Omer, Arina D. [1 ,2 ,3 ]
Janas, Maja M. [1 ,2 ,3 ]
Novina, Carl D. [1 ,2 ,3 ]
机构：
[1] Harvard Univ, Sch Med, Dana Farber Canc Inst, Dept Canc Immunol & AIDS, Boston, MA 02115 USA
[2] Harvard Univ, Sch Med, Dept Pathol, Boston, MA 02115 USA
[3] Broad Inst MIT & Harvard, Cambridge, MA 02141 USA
来源：
MOLECULAR CELL | 2009年 / 35卷 / 06期
关键词：
CAENORHABDITIS-ELEGANS; INITIATION-FACTOR; IN-VITRO; PROTEIN; MECHANISMS; COMPLEX;
D O I：
10.1016/j.molcel.2009.09.003
中图分类号：
Q5 [生物化学]; Q7 [分子生物学];
学科分类号：
071010 ; 081704 ;
摘要：
In this issue of Molecular Cell, Fabian et al. (2009) demonstrate that in cell-free extracts from mouse Krebs-2 ascites, microRNA-mediated translational repression precedes target mRNA deadenylation, and identify GW182, PABP, and deadenylase subunits CAR and CCR4 as factors required for deadenylation.
引用
下载
收藏
页码：739 / 740
页数：2
相关论文
共 50 条
  • [21] Mechanisms of microRNA-mediated gene regulation
    Shuang Zhao
    Mo-Fang Liu
    Science in China Series C: Life Sciences, 2009, 52 : 1111 - 1116
  • [22] A Specialized Mechanism of MicroRNA-mediated Translation in Quiescence
    Vasudevan, Shobha
    Bukhari, Syed Irfan Ahmed
    Truesdell, Samuel Spencer
    Lee, Sooncheol
    Kollu, Swapna
    Classon, Anthony
    Boukhali, Myriam
    Jain, Esha
    Yanagiya, Akiko
    Sadyrev, Ruslan
    Haas, Wilhelm
    FASEB JOURNAL, 2016, 30
  • [23] microRNA-mediated regulation in fruit quality
    Huang, Xing
    Xia, Rui
    Liu, Yuanlong
    CURRENT OPINION IN FOOD SCIENCE, 2022, 46
  • [24] Mechanisms of microRNA-mediated gene regulation
    Nilsen, Timothy W.
    FASEB JOURNAL, 2007, 21 (05): : A92 - A92
  • [25] MicroRNA-mediated regulation of KRAS in cancer
    Kim, Minlee
    Slack, Frank J.
    JOURNAL OF HEMATOLOGY & ONCOLOGY, 2014, 7
  • [26] MicroRNA-mediated regulation of KRAS in cancer
    Minlee Kim
    Frank J Slack
    Journal of Hematology & Oncology, 7
  • [27] Epigenetic and microRNA-mediated regulation in diabetes
    Muhonen, Pirkko
    Holthofer, Harry
    NEPHROLOGY DIALYSIS TRANSPLANTATION, 2009, 24 (04) : 1088 - 1096
  • [28] Mechanisms of microRNA-mediated gene regulation
    ZHAO Shuang & LIU Mo-Fang· State Key Laboratory of Molecular Biology
    Science China Life Sciences, 2009, 52 (12) : 1111 - 1116
  • [29] MicroRNA-mediated regulation of the angiogenic switch
    Anand, Sudarshan
    Cheresh, David A.
    CURRENT OPINION IN HEMATOLOGY, 2011, 18 (03) : 171 - 176
  • [30] Mechanisms of microRNA-mediated gene regulation
    Zhao Shuang
    Liu Mo-Fang
    SCIENCE IN CHINA SERIES C-LIFE SCIENCES, 2009, 52 (12): : 1111 - 1116
12345