Interaction between chlorophyll a and β-cyclodextrin derivatives in aqueous solutions -: Spectroscopic and calorimetric study

被引：18
|
作者：
Agostiano, A
Catucci, L
Castagnolo, M
Colangelo, D
Cosma, P
Fini, P
Della Monica, M
机构：
[1] CNR, Ctr Studi Chim Fis Interaz Luce Mat, I-70126 Bari, Italy
[2] Univ Bari, Dipartmento Chim, I-70126 Bari, Italy
来源：
JOURNAL OF THERMAL ANALYSIS AND CALORIMETRY | 2002年 / 70卷 / 01期
关键词：
chlorophyll a; cyclodextrins; photodynamic therapy;
D O I：
10.1023/A:1020601600086
中图分类号：
O414.1 [热力学];
学科分类号：
摘要：
Cyclodextrins (CDs) are widely used as delivery systems of poorly water soluble drugs in pharmacological applications. The delivery system produces an increase of aqueous solubility of the drug and significant modifications in its physico-chemical and pharmacological properties. In this paper we report the results of our study on aqueous solutions of chlorophyll a, a natural pigment useful as sensitizer in the photodynamic therapy, and two CDs: hydroxypropyl-beta-cyclodextrin and heptakis(2,6-di-O-methyl)-beta-cyclodextrin. The interactions between chlorophyll and CDs and the effect produced by the presence of the CDs on the aggregation of chlorophyll were studied by calorimetric and UV-Vis spectrophotometric measurements respectively.
引用
收藏
页码：115 / 122
页数：8
相关论文
共 50 条
  • [1] Interaction between chlorophyll a and b-cyclodextrin derivatives in aqueous solutions
    A. Agostiano
    L. Catucci
    M. Castagnolo
    D. Colangelo
    P. Cosma
    P. Fini
    M. Della Monica
    [J]. Journal of Thermal Analysis and Calorimetry, 2002, 70 : 115 - 122
  • [2] Thermodynamics of the interaction between antihistamines with native and hydroxypropyl-cyclodextrin derivatives in aqueous solutions
    Alvarez-Lopez, Enrique
    Perez-Casas, Silvia
    [J]. JOURNAL OF CHEMICAL THERMODYNAMICS, 2013, 67 : 197 - 202
  • [3] Study of the interaction of β-cyclodextrin with albendazole in aqueous solutions
    Stepniak, A.
    Buczkowski, A.
    Zavodnik, L.
    Belica-Pacha, S.
    Palecz, B.
    [J]. JOURNAL OF MOLECULAR LIQUIDS, 2017, 248 : 19 - 23
  • [4] Thermodynamics of the interaction of alpha-cyclodextrin with monocarboxylic acids in aqueous solutions: A calorimetric study at 25 degrees C
    Castronuovo, G
    Elia, V
    Fessas, D
    Velleca, F
    Viscardi, G
    [J]. CARBOHYDRATE RESEARCH, 1996, 287 (02) : 127 - 138
  • [5] Spectroscopic and calorimetric study of DNA interaction with a new series of actinocin derivatives
    Maleev, V
    Semenov, A
    Kruglova, E
    Bolbukh, T
    Gasan, A
    Bereznyak, E
    Shestopalova, A
    [J]. JOURNAL OF MOLECULAR STRUCTURE, 2003, 645 (2-3) : 145 - 158
  • [6] Factors determining the formation of complexes between α-cyclodextrin and alkylated substances in aqueous solutions:: a calorimetric study at 25 °C
    Castronuovo, G
    Elia, V
    Iannone, A
    Niccoli, M
    Velleca, F
    [J]. CARBOHYDRATE RESEARCH, 2000, 325 (04) : 278 - 286
  • [7] Spectroscopic and calorimetric studies on the interaction between PAMAM G4-OH and 5-fluorouracil in aqueous solutions
    Buczkowski, Adam
    Urbaniak, Pawel
    Piekarski, Henryk
    Palecz, Bartlomiej
    [J]. SPECTROCHIMICA ACTA PART A-MOLECULAR AND BIOMOLECULAR SPECTROSCOPY, 2017, 171 : 401 - 405
  • [8] UV SPECTROSCOPIC STUDY OF THE INTERACTION BETWEEN ALPHA-CYCLODEXTRIN, BETA-CYCLODEXTRIN, AND GAMMA-CYCLODEXTRIN AND PYRIDINE-DERIVATIVES
    RAMUSINO, MC
    RUFINI, L
    MUSTAZZA, C
    [J]. JOURNAL OF INCLUSION PHENOMENA AND MOLECULAR RECOGNITION IN CHEMISTRY, 1993, 15 (04): : 359 - 368
  • [9] Thermodynamics of the interaction between hydroxypropyl-α-cyclodextrin and alkanols in aqueous solutions
    Vega-Rodriguez, A
    Piñeiro, A
    Perez-Casas, S
    [J]. THERMOCHIMICA ACTA, 2003, 405 (01) : 109 - 115
  • [10] Enthalpies of interaction between cellobiose and the derivatives of cellulose in aqueous solutions
    M. V. Radugin
    T. N. Lebedeva
    A. N. Prusov
    A. G. Zakharov
    [J]. Russian Journal of Physical Chemistry A, 2011, 85 : 1863 - 1865
12345