KCNE1 Modulates the Sensitivity of Kv7.1 to Polyunsaturated Fatty Acids

被引：0
|
作者：
Liin, Sara I. [1 ]
Schmitt, Nicole [2 ]
Larsson, Johan [1 ]
Haerlin, Frida Starck [1 ]
Bentzen, Bo H. [2 ]
Larsson, H. Peter [1 ]
Elinder, Fredrik [3 ]
机构：
[1] Univ Miami, Miami, FL USA
[2] Univ Copenhagen, Copenhagen, Denmark
[3] Linkoping Univ, Linkoping, Sweden
来源：
BIOPHYSICAL JOURNAL | 2014年 / 106卷 / 02期
关键词：
D O I：
10.1016/j.bpj.2013.11.831
中图分类号：
Q6 [生物物理学];
学科分类号：
071011 ;
摘要：
引用
收藏
页码：143A / 143A
页数：1
相关论文
共 50 条
  • [31] Kv7.1 (KCNQ1) properties and channelopathies
    Peroz, David
    Rodriguez, Nicolas
    Choveau, Frank
    Baro, Isabelle
    Merot, Jean
    Loussouarn, Gildas
    JOURNAL OF PHYSIOLOGY-LONDON, 2008, 586 (07): : 1785 - 1789
  • [32] A KCNE1 C-Terminus Long QT Mutation Disrupts a Crucial Interaction with the Kv7.1 Coiled-Coil Helix C and Reduces IKS Channel Expression
    Dvir, Meidan
    Shaham, Dana
    Haitin, Yoni
    Cohen, Enbal Ben-Tal
    Hirsch, Joel
    Attali, Bernard
    BIOPHYSICAL JOURNAL, 2011, 100 (03) : 573 - 573
  • [33] The endocannabinoid ARA-S acts as an endogenous rescuing factor of Kv7.1/KCNE1 carrying Long QT syndrome mutations and paves the way for drug development strategies
    Inigo, I. Hiniesto
    Sridhar, A.
    Lundholm, S. A.
    Liin, S., I
    CARDIOVASCULAR RESEARCH, 2024, 120
  • [34] KCNE1-Dependent Sumoylation of KV7.1 Subunits Determines the Voltage-Dependence of Cardiac IKs Channels
    Xiong, Dazhi
    Li, Tian
    Plant, Leigh D.
    Goldstein, Steve A. N.
    BIOPHYSICAL JOURNAL, 2017, 112 (03) : 163A - 163A
  • [35] Rescue of loss-of-function long QT syndrome-associated mutations in KV7.1/KCNE1 by the endocannabinoid N-arachidonoyl-L-serine (ARA-S)
    Hiniesto-Inigo, Irene
    Sridhar, Akshay
    Louradour, Julien
    Cruz, Alicia
    Lundholm, Siri
    Jauregi-Miguel, Amaia
    Giannetti, Federica
    Sala, Luca
    Odening, Katja E.
    Larsson, H. Peter
    Ottosson, Nina E.
    Liin, Sara I.
    BRITISH JOURNAL OF PHARMACOLOGY, 2025,
  • [36] Rational Design of Fatty Acid Analogues Targeting the Cardiac KV7.1 Channel
    Liin, Sara I.
    BIOPHYSICAL JOURNAL, 2021, 120 (03) : 111A - 111A
  • [37] The unconventional biogenesis of Kv7.1-KCNE1 complexes
    Oliveras, Anna
    Serrano-Novillo, Clara
    Moreno, Cristina
    de la Cruz, Alicia
    Valenzuela, Carmen
    Soeller, Christian
    Comes, Nuria
    Felipe, Antonio
    SCIENCE ADVANCES, 2020, 6 (14):
  • [38] Hormonal Signaling Actions on Kv7.1 (KCNQ1) Channels
    Thompson, Emely
    Eldstrom, Jodene
    Fedida, David
    ANNUAL REVIEW OF PHARMACOLOGY AND TOXICOLOGY, VOL 61, 2021, 2021, 61 : 381 - 400
  • [39] Structure of KCNE1 and implications for how it modulates the KCNQ1 potassium channel
    Kang, Congbao
    Tian, Changlin
    Soennichsen, Frank D.
    Smith, Jarrod A.
    Meiler, Jens
    George, Alfred L., Jr.
    Vanoye, Carlos G.
    Kim, Hak Jun
    Sanders, Charles R.
    BIOCHEMISTRY, 2008, 47 (31) : 7999 - 8006
  • [40] Polyunsaturated fatty acids modify the gating of Kv channels
    Moreno, Cristina
    Macias, Alvaro
    Prieto, Angela
    De La Cruz, Alicia
    Valenzuela, Carmen
    FRONTIERS IN PHARMACOLOGY, 2012, 3
12345