Pridopidine, a selective Sigma-1 receptor (S1R) agonist promotes neuroprotection in ALS models

被引:0
|
作者
Geva, Michal [1 ]
Wang, Shao-Ming [2 ,3 ,5 ]
Wu, Hsiang-En [2 ,4 ]
Ankol, Lior [6 ,7 ]
Ionescu, Ariel [6 ,7 ]
Gradus-Pery, Tal [6 ,7 ]
Gershoni-Emek, Noga [1 ]
Goldberg, Y. Paul [1 ]
Su, Tsung-Ping [2 ]
Perlson, Eran [6 ,7 ]
Hayden, Michael R. [1 ,8 ]
机构
[1] Prilenia Therapeut, Herzliyya, Israel
[2] Natl Inst Drug Abuse, Natl Inst Hlth, Cellular Pathobiol Sect, Integrat Neurosci Res Branch,Intramural Res Progr, Baltimore, MD USA
[3] China Med Univ, Grad Inst Biomed Sci, Taichung, Taiwan
[4] China Med Univ, Neurosci & Brain Dis Ctr, Taichung, Taiwan
[5] China Med Univ Hosp, Dept Neurol, Taichung, Taiwan
[6] Sagol Sch Neurosci, Tel Aviv, Israel
[7] Sackler Sch Med, Tel Aviv, Israel
[8] Univ British Columbia, CMMT, Vancouver, BC, Canada
关键词
D O I
暂无
中图分类号
R74 [神经病学与精神病学];
学科分类号
摘要
6
引用
收藏
页码:S4 / S5
页数:2
相关论文
共 50 条
  • [31] Sigma-1 receptor agonist fluvoxamine for delirium in patients with Alzheimer's disease
    Furuse, Tsutomu
    Hashimoto, Kenji
    ANNALS OF GENERAL PSYCHIATRY, 2010, 9
  • [32] Sigma-1 receptor agonist fluvoxamine for delirium in patients with Alzheimer's disease
    Tsutomu Furuse
    Kenji Hashimoto
    Annals of General Psychiatry, 9
  • [33] Role of the Sigma-1 receptor in Amyotrophic Lateral Sclerosis (ALS)
    Mavlyutov, Timur A.
    Guo, Lian-Wang
    Epstein, Miles L.
    Ruoho, Arnold E.
    JOURNAL OF PHARMACOLOGICAL SCIENCES, 2015, 127 (01) : 10 - 16
  • [34] The Sigma-1 Receptor-A Therapeutic Target for the Treatment of ALS?
    Mavlyutov, Timur A.
    Baker, Erin M.
    Losenegger, Tasher M.
    Kim, Jaimie R.
    Torres, Brian
    Epstein, Miles L.
    Ruoho, Arnold E.
    SIGMA RECEPTORS: THEIR ROLE IN DISEASE AND AS THERAPEUTIC TARGETS, 2017, 964 : 255 - 265
  • [35] LACK OF SIGMA-1 RECEPTOR EXACERBATES ALS PROGRESSION IN MICE
    Mavlyutov, T. A.
    Epstein, M. L.
    Verbny, Y. I.
    Huerta, M. S.
    Zaitoun, I.
    Ziskind-Conhaim, L.
    Ruoho, A. E.
    NEUROSCIENCE, 2013, 240 : 129 - 134
  • [36] Comments to "Fluvoxamine and long COVID-19: a new role for sigma-1 receptor (S1R) agonists" by Khani and Entezari-Maleki
    Hashimoto, Yaeko
    Suzuki, Takuji
    Hashimoto, Kenji
    MOLECULAR PSYCHIATRY, 2022, 27 (09) : 3563 - 3564
  • [37] Comments to “Fluvoxamine and long COVID-19: a new role for sigma-1 receptor (S1R) agonists” by Khani and Entezari-Maleki
    Yaeko Hashimoto
    Takuji Suzuki
    Kenji Hashimoto
    Molecular Psychiatry, 2022, 27 : 3563 - 3564
  • [38] The sigma-1 receptor mediates the beneficial effects of pridopidine in a mouse model of Huntington disease
    Ryskamp, Daniel
    Wu, Jun
    Geva, Michal
    Kusko, Rebecca
    Grossman, Iris
    Hayden, Michael
    Bezprozvanny, Ilya
    NEUROBIOLOGY OF DISEASE, 2017, 97 : 46 - 59
  • [39] Viewpoints Sigma-1 receptor agonist fluvoxamine for multiple sclerosis
    Hashimoto, Kenji
    BRAIN BEHAVIOR & IMMUNITY-HEALTH, 2024, 37
  • [40] Clinical implications of using fluvoxamine, a sigma-1 receptor agonist
    Hashimoto, K.
    INTERNATIONAL JOURNAL OF NEUROPSYCHOPHARMACOLOGY, 2010, 13 : 250 - 250