Stereochemical studies by molecular palpation

被引：4
|
作者：
Locci, E
Bartik, K
Segebarth, N
Luhmer, M
Reisse, J
机构：
[1] Free Univ Brussels, B-1050 Brussels, Belgium
[2] Univ Cagliari, Dipartimento Sci Chim, I-09042 Cagliari, Italy
[3] Free Univ Brussels, Dept Chim, Lab RMN Haute Resolut, B-1050 Brussels, Belgium
来源：
JOURNAL OF PHYSICAL ORGANIC CHEMISTRY | 2004年 / 17卷 / 09期
关键词：
NMR spectroscopy; xenon; conformational equilibrium; cyclohexanol; molecular palpation;
D O I：
10.1002/poc.795
中图分类号：
O62 [有机化学];
学科分类号：
070303 ; 081704 ;
摘要：
The conformational equilibrium of cyclohexanol was investigated by Xe-129 NMR spectroscopy. While the classical NMR approach focuses on a carbon or proton atom belonging to the molecule under investigation, in our Xe-129 NMR methodology we use the xenon atom as an external spy. Xenon is able to monitor the interconversion between the axial and the equatorial isomers of cyclohexanol. The conformational equilibrium constant was estimated and is in excellent agreement with the values obtained by H-1 and C-13 NMR. Copyright (C) 2004 John Wiley Sons, Ltd.
引用
收藏
页码：787 / 792
页数：6
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