Development imaging and experimental model for study pathogenesis and treatment efficacy of postmastectomy lymphedema

被引:4
|
作者
Galanzha, EI [1 ]
Tuchin, VV [1 ]
Solov'eva, AV [1 ]
Stepanova, TV [1 ]
Brill, GE [1 ]
Zharov, VP [1 ]
机构
[1] Saratov NG Chernyshevskii State Univ, Saratov 410071, Russia
来源
OPTICAL DIAGNOSTICS AND SENSING OF BIOLOGICAL FLUIDS AND GLUCOSE AND CHOLESTEROL MONITORING II | 2002年 / 4624卷
关键词
model of lymphedema; transmission microscopy; lymph and blood microcirculation;
D O I
10.1117/12.468315
中图分类号
R318 [生物医学工程];
学科分类号
0831 ;
摘要
The experimental model was created during an abdominal dissection of the rat mesentery and ligation of the collecting vein of mesentery. It was found that mesentery edema was developed for 20-30 min. Simultaneously monitoring of main the parameters of blood and lymph flow revealed significant increasing of interstitial water amount (up to 3 times), reduction of blood microcirculation, increasing of blood vessels permeability, decreasing of lymph microvessels diameter, phasics contractions, and lymph flow velocity.
引用
收藏
页码:123 / 129
页数:7
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