Basic Anatomy and Physiology of Pain Pathways

被引:79
|
作者
Bourne, Sarah [1 ]
Machado, Andre G. [2 ]
Nagel, Sean J. [2 ]
机构
[1] Cleveland Clin, Dept Neurosurg, Cleveland, OH 44195 USA
[2] Cleveland Clin, Lerner Coll Med, Ctr Neurol Restorat, Dept Neurosurg, Cleveland, OH 44195 USA
关键词
Hyperalgesia; Allodynia; Peripheral sensitization; Spino-thalamic tract; Gait control theory; Descending systems; ELECTRICAL-STIMULATION; VENTRAL ROOTS; MECHANICAL STIMULATION; PERIAQUEDUCTAL GRAY; UNMYELINATED FIBERS; DORSAL-HORN; CELL GROUP; C-FIBERS; RAT; NEURONS;
D O I
10.1016/j.nec.2014.06.001
中图分类号
R74 [神经病学与精神病学];
学科分类号
摘要
This article provides an integrated review of the basic anatomy and physiology of the pain processing pathways. The transmission and parcellation of noxious stimuli from the peripheral nervous system to the central nervous system is discussed. In addition, the inhibitory and excitatory systems that regulate pain along with the consequences of dysfunction are considered.
引用
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页码:629 / +
页数:11
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