Somatic cell nuclear transfer

被引:364
|
作者
Wilmut, I [1 ]
Beaujean, N
de Sousa, PA
Dinnyes, A
King, TJ
Paterson, LA
Wells, DN
Young, LE
机构
[1] Roslin Inst, Roslin EH25 9PS, Midlothian, Scotland
[2] AgResearch, Hamilton, New Zealand
关键词
D O I
10.1038/nature01079
中图分类号
O [数理科学和化学]; P [天文学、地球科学]; Q [生物科学]; N [自然科学总论];
学科分类号
07 ; 0710 ; 09 ;
摘要
Cloning by nuclear transfer from adult somatic cells is a remarkable demonstration of developmental plasticity. When a nucleus is placed in oocyte cytoplasm, the changes in chromatin structure that govern differentiation can be reversed, and the nucleus can be made to control development to term.
引用
收藏
页码:583 / 586
页数:4
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