Targeting Kv1.3 channels on T cells

被引:0
|
作者
Carney, Ellen F.
机构
[1] Nature Reviews Rheumatology,
关键词
D O I
10.1038/s41584-020-00560-4
中图分类号
R5 [内科学];
学科分类号
1002 ; 100201 ;
摘要
引用
收藏
页码:68 / 68
页数:1
相关论文
共 50 条
  • [41] Kv1.3 channels are a therapeutic target for T cell-mediated autoimmune diseases
    Beeton, Christine
    Wulff, Heike
    Standifer, Nathan E.
    Azam, Philippe
    Mullen, Katherine M.
    Pennington, Michael W.
    Kolski-Andreaco, Aaron
    Wei, Eric
    Grino, Alexandra
    Counts, Debra R.
    Wang, Ping H.
    LeeHealey, Christine J.
    Andrews, Brian S.
    Sankaranarayanan, Ananthakrishnan
    Homerick, Daniel
    Roeck, Werner W.
    Tehranzadeh, Jamshid
    Stanhope, Kimber L.
    Zimin, Pavel
    Havel, Peter J.
    Griffey, Stephen
    Knaus, Hans-Guenther
    Nepom, Gerald T.
    Gutman, George A.
    Calabresi, Peter A.
    Chandy, K. George
    [J]. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA, 2006, 103 (46) : 17414 - 17419
  • [42] Kv1.3 channels: therapeutic target for T cell-mediated autoimmune diseases
    Beeton, C.
    Wulff, H.
    Standifer, N. E.
    Mullen, K. M.
    Azam, P.
    Kolski-Andreaco, A.
    Wei, E.
    Grino, A.
    Counts, D. R.
    Wang, P. H.
    LeeHealey, C. J.
    Andrews, B. S.
    Pennington, M. W.
    Knaus, H. G.
    Nepom, G. T.
    Gutman, G. A.
    Calabresi, P. A.
    Chandy, K. G.
    [J]. JOURNAL OF IMMUNOLOGY, 2006, 176 : S148 - S148
  • [43] Targeting disease-specific autoreactive T cells with Kv1.3 blockers: A new therapy for autoimmune diseases
    Wulff, H
    Mullen, K
    Beeton, C
    Wang, P
    Counts, D
    Calabresi, PA
    Chandy, KG
    [J]. BIOPHYSICAL JOURNAL, 2005, 88 (01) : 21A - 21A
  • [44] Kv1.3 channels: Therapeutic target for T cell-mediated autoimmune diseases
    Monaghan, Kevin P.
    Beeton, Christine
    Wulff, Heike
    Calabresi, Peter
    Chandy, George K.
    [J]. NEUROLOGY, 2007, 68 (12) : A339 - A340
  • [45] The C-terminal HRET sequence of Kv1.3 regulates gating rather than targeting of Kv1.3 to the plasma membrane
    Orsolya Voros
    Orsolya Szilagyi
    András Balajthy
    Sándor Somodi
    Gyorgy Panyi
    Péter Hajdu
    [J]. Scientific Reports, 8
  • [46] Staurosporine directly blocks Kv1.3 channels expressed in Chinese hamster ovary cells
    Choi, JS
    Hahn, SJ
    Rhie, DJ
    Jo, YH
    Kim, MS
    [J]. NAUNYN-SCHMIEDEBERGS ARCHIVES OF PHARMACOLOGY, 1999, 359 (04) : 256 - 261
  • [47] The C-terminal HRET sequence of Kv1.3 regulates gating rather than targeting of Kv1.3 to the plasma membrane
    Voros, Orsolya
    Szilagyi, Orsolya
    Balajthy, Andras
    Somodi, Sandor
    Panyi, Gyorgy
    Hajdu, Peter
    [J]. SCIENTIFIC REPORTS, 2018, 8
  • [48] Microglia Kv1.3 channels contribute to their ability to kill neurons
    Fordyce, CB
    Jagasia, R
    Zhu, XP
    Schlichter, LC
    [J]. JOURNAL OF NEUROSCIENCE, 2005, 25 (31): : 7139 - 7149
  • [49] Selective downregulation of human Kv1.3 channels by PKA I
    Kuras, Zerrin
    Kucher, Vladimir
    Neumeier, Lisa
    Dillehay, Kelsey
    Conforti, Laura
    [J]. FASEB JOURNAL, 2010, 24
  • [50] 18β-Glycyrrhetinic acid potently inhibits Kv1.3 potassium channels and T cell activation in human Jurkat T cells
    Fu, Xiao-Xing
    Du, Li-Li
    Zhao, Ning
    Dong, Qian
    Liao, Yu-Hua
    Du, Yi-Mei
    [J]. JOURNAL OF ETHNOPHARMACOLOGY, 2013, 148 (02) : 647 - 654