Regioselective N/C-Heterocyclization of Allenylindium Bromide Across Aryl Azides: One-Pot Synthesis of 5-Methyl-1,2,3-triazoles

被引：12

作者：

Banday, Abid H. ^{[1
]}

Hruby, Victor J. ^{[1
]}

机构：

[1] Univ Arizona, Dept Chem & Biochem, Tucson, AZ 85721 USA

来源：

SYNLETT | 2014年 / 25卷 / 13期

关键词：

heterocyclization; aryl azides; 1,2,3-triazoles; allenylindium bromide; regioselective reactions; RUTHENIUM-CATALYZED CYCLOADDITION; TERMINAL ALKYNES; RAPID SYNTHESIS; TRIAZOLES; MECHANISM; LIGATION;

D O I：

10.1055/s-0034-1378327

中图分类号：

O62 [有机化学];

学科分类号：

070303 ; 081704 ;

摘要：

An unprecedented, one-pot regioselective synthesis of 1,5-disubstituted 1,2,3-triazoles through N/C-heterocyclization of allenylindium bromide across aryl azides is described. The synthesis is carried out under mild conditions in aqueous medium and proceeds regioselectively in moderate to good yields.

引用

页码：1859 / 1862

页数：4

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