Regioselective N/C-Heterocyclization of Allenylindium Bromide Across Aryl Azides: One-Pot Synthesis of 5-Methyl-1,2,3-triazoles

被引：12
|
作者：
Banday, Abid H. [1 ]
Hruby, Victor J. [1 ]
机构：
[1] Univ Arizona, Dept Chem & Biochem, Tucson, AZ 85721 USA
来源：
SYNLETT | 2014年 / 25卷 / 13期
关键词：
heterocyclization; aryl azides; 1,2,3-triazoles; allenylindium bromide; regioselective reactions; RUTHENIUM-CATALYZED CYCLOADDITION; TERMINAL ALKYNES; RAPID SYNTHESIS; TRIAZOLES; MECHANISM; LIGATION;
D O I：
10.1055/s-0034-1378327
中图分类号：
O62 [有机化学];
学科分类号：
070303 ; 081704 ;
摘要：
An unprecedented, one-pot regioselective synthesis of 1,5-disubstituted 1,2,3-triazoles through N/C-heterocyclization of allenylindium bromide across aryl azides is described. The synthesis is carried out under mild conditions in aqueous medium and proceeds regioselectively in moderate to good yields.
引用
收藏
页码：1859 / 1862
页数：4
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