Central nervous system relapse in multiple myeloma: An unusual complication

被引:0
|
作者
Vasudevan, Arun [1 ]
Narayanan, Geetha [1 ,3 ]
Nayak, Nileena [2 ]
机构
[1] Reg Canc Ctr, Dept Med Oncol, Thiruvananthapuram, Kerala, India
[2] Reg Canc Ctr, Dept Pathol, Thiruvananthapuram, Kerala, India
[3] Reg Canc Ctr, Dept Med Oncol, Thiruvananthapuram 695011, Kerala, India
关键词
Central nervous system; cerebrospinal fluid positivity; multiple myeloma; INTRATHECAL CHEMOTHERAPY; POMALIDOMIDE; INVOLVEMENT;
D O I
10.4103/ijh.ijh_10_21
中图分类号
R5 [内科学];
学科分类号
1002 ; 100201 ;
摘要
Central nervous system involvement in multiple myeloma (MM) is rare and carries a very poor prognosis. We report the case of a 62-year-old man diagnosed with MM who received induction chemotherapy with bortezomib, cyclophosphamide, and dexamethasone and achieved very good partial response. He developed seizures and altered sensorium while on maintenance chemotherapy. Magnetic resonance imaging of the brain showed leptomeningeal enhancement, and cerebrospinal fluid cytology was positive for plasma cells. His general condition worsened, and he died before starting any specific treatment.
引用
收藏
页码:186 / 188
页数:3
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