Antigenotoxic and Antioxidant Activities of Fruit Extracts from (Tunisian) Pistacia Lentiscus

被引：4
|
作者：
Abdelwahed, A. [2 ]
Bhouri, W. [2 ]
Neffati, A. [2 ]
Ben Sghaier, M. [2 ]
Boubaker, J. [2 ]
Bouhlel, I. [2 ]
Skandrani, I. [2 ]
Ben Ammar, R. [2 ]
Ghedira, K. [2 ]
Chekir-Ghedira, L. [1 ]
机构：
[1] Fac Med Dent, Lab Biol Mol & Cellulaire, Monastir 5000, Tunisia
[2] Fac Pharm, Unite Pharmacognosie Biol Mol UR 99 07 03, Monastir 5000, Tunisia
来源：
FOOD SCIENCE AND TECHNOLOGY INTERNATIONAL | 2009年 / 15卷 / 03期
关键词：
Pistacia lentiscus; SOS chromotest; mutagenic effect; antimutagenic activity; antioxidant activity; MEDICINAL-PLANTS; PHENOLIC-COMPOUNDS; XANTHINE-OXIDASE; SOS CHROMOTEST; MUTAGENICITY; FLAVONOIDS; CARCINOGENESIS; INHIBITORS; FRACTIONS; NETWORK;
D O I：
10.1177/1082013208339705
中图分类号：
O69 [应用化学];
学科分类号：
081704 ;
摘要：
Genotoxic and antigenotoxic activities against direct acting mutagen nifuroxazide, and indirect acting genotoxin aflatoxine B1 (AFB1) of extracts prepared from fruits of Pistacia lentiscus, were studied using the SOS chromotest with Escherichia coli PQ 37 as a tester organism. It was found that different extracts showed no genotoxicity when tested with E. coli PQ 37 strain either with or without microsomal extract. On the other hand, our results showed that ethyl acetate fraction and total oligomers flavonoids (TOF) extract obtained from P. lentiscus significantly decreased the genotoxicicity induced by AFB1 (10 mu g/assay) and nifuroxazide (20 mu g/assay). In addition to antigenotoxic activity, these extracts showed an important free radical scavenging activity towards the 2,2-diphenyl-2-picrylhydrazyl (DPPH) free radical and an important antioxidant activity using xanthine/xanthine oxidase system.
引用
下载
收藏
页码：215 / 222
页数：8
相关论文
共 50 条
  • [31] The healing effect of Pistacia lentiscus fruit oil on laser burn
    Ben Khedir, Sameh
    Bardaa, Sana
    Chabchoub, Naourez
    Moalla, Dorsaf
    Sahnoun, Zouheir
    Rebai, Tarek
    PHARMACEUTICAL BIOLOGY, 2017, 55 (01) : 1407 - 1414
  • [32] The effects of aqueous extracts prepared from the leaves of Pistacia lentiscus in experimental liver disease
    Ljubuncic, P
    Song, H
    Cogan, U
    Azaizeh, H
    Bomzon, A
    JOURNAL OF ETHNOPHARMACOLOGY, 2005, 100 (1-2) : 198 - 204
  • [33] Pomological Analyses, Physicochemical Properties, Antioxidant Activities, and Microbial Inhibition of Pistacia lentiscus Berries During Ripening
    Ayad, Rabha
    Amessis-Ouchemoukh, Nadia
    Guenaoui, Nawel
    Sadou, Dyhia
    Madani, Khodir
    Ouchemoukh, Salim
    ERWERBS-OBSTBAU, 2023, 65 (05): : 1557 - 1569
  • [34] Pomological Analyses, Physicochemical Properties, Antioxidant Activities, and Microbial Inhibition of Pistacia lentiscus Berries During Ripening
    Rabha Ayad
    Nadia Amessis-Ouchemoukh
    Nawel Guenaoui
    Dyhia Sadou
    Khodir Madani
    Salim Ouchemoukh
    Erwerbs-Obstbau, 2023, 65 : 1557 - 1569
  • [35] Antioxidant and Antigenotoxic Activity of Bioactive Extracts from Corn Tassel
    王丽春
    余雅芹
    方敏
    占才贵
    潘红艳
    吴永宁
    宫智勇
    Current Medical Science, 2014, (01) : 131 - 136
  • [36] NMR metabolic profiling of Greek Pistacia lentiscus leaves and fruit extracts for the identification of biomarkers with skin beneficial effects
    Cheilari, A.
    Papalexis, P.
    Vontzalidou, A.
    Dina, E.
    Smyrnioudis, I
    Aligiannis, N.
    PLANTA MEDICA, 2019, 85 (18) : 1466 - 1466
  • [37] Chemical composition and antioxidant activities of cold pressed lentisc (Pistacia lentiscus L.) seed oil
    Daoued, K. B.
    Chouaibi, M.
    Gaout, N.
    Haj, O. Bel
    Hamdi, S.
    RIVISTA ITALIANA DELLE SOSTANZE GRASSE, 2016, 93 (01): : 31 - 38
  • [38] Fatty acids, 4-desmethylsterols, and triterpene alcohols from Tunisian lentisc (Pistacia lentiscus) fruits
    Trabelsi, Hajer
    Sakouhi, Faouzi
    Renaud, Justin
    Villeneuve, Pierre
    Khouja, Mohamed L.
    Mayer, Paul
    Boukhchina, Sadok
    EUROPEAN JOURNAL OF LIPID SCIENCE AND TECHNOLOGY, 2012, 114 (08) : 968 - 973
  • [39] Antioxidant activities of the extracts from chestnut flower, leaf, skins and fruit
    Barreira, Joao C. M.
    Ferreira, Isabel C. F. R.
    Oliveira, M. Beatriz P. P.
    Pereira, Jose Alberto
    FOOD CHEMISTRY, 2008, 107 (03) : 1106 - 1113
  • [40] LC-ESI-QTOF-MS, MS/MS Analysis of Glycerophospholipid Species in Three Tunisian Pistacia lentiscus Fruit Populations
    Trabelsi, Hajer
    Renaud, Justin
    Herchi, Wahid
    Khouja, Mohamed L.
    Boukhchina, Sadok
    Mayer, Paul
    JOURNAL OF THE AMERICAN OIL CHEMISTS SOCIETY, 2013, 90 (05) : 611 - 618
12345