Highly Enantioselective Carbonyl-ene Reactions Catalyzed by In(III)-PyBox Complex

被引：60
|
作者：
Zhao, Jun-Feng [1 ]
Tsui, Hoi-Yan [1 ]
Wu, Pei-Jia [1 ]
Lu, Jun [1 ]
Loh, Teck-Peng [1 ]
机构：
[1] Nanyang Technol Univ, Sch Math & Phys Sci, Div Chem & Biol Chem, Singapore 637371, Singapore
来源：
JOURNAL OF THE AMERICAN CHEMICAL SOCIETY | 2008年 / 130卷 / 49期
关键词：
D O I：
10.1021/ja807501a
中图分类号：
O6 [化学];
学科分类号：
0703 ;
摘要：
A highly enantioselective carbonyl-ene reaction catalyzed by In(III)-pybox is described. Both 1, 1-disubstituted alkenes and 1,1,2-trisubstituted alkenes proceeded smoothly to give the ene products in high yields up to 97% and with excellent diastereoselectivity and enantioselectivities up to > 99:1 and 99%, respectively.
引用
收藏
页码：16492 / +
页数：3
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