Fluorenone based fluorescent probe for selective "turn-on" detection of pyrophosphate and alanine

被引:16
|
作者
Thangadurai, T. Daniel [1 ]
Nithya, I. [1 ]
Manjubaashini, N. [1 ]
Bhuvanesh, N. [2 ]
Bharathi, G. [3 ]
Nandhakumar, R. [2 ]
Nataraj, D. [3 ]
机构
[1] Sri Ramakrishana Engn Coll, Dept Nanosci & Technol, Coimbatore 641022, Tamil Nadu, India
[2] Karunya Univ, Dept Chem, Coimbatore 641115, Tamil Nadu, India
[3] Bharathiar Univ, Dept Phys, Coimbatore 641046, Tamil Nadu, India
关键词
Fluorenone; Biological entities; H-bonds; Stoichiometry; Zwitterionic form; AMINO-ACID; ANION; ZINC; CADMIUM; BINDING; SENSOR; RECOGNITION; DERIVATIVES; EMISSION; FLUORIDE;
D O I
10.1016/j.saa.2017.11.013
中图分类号
O433 [光谱学];
学科分类号
0703 ; 070302 ;
摘要
To sense biologically important entities with different size and dimensions, a fluorenone based fluorescent receptor was designed and synthesized. Probe 1 displayed a distinct fluorescence enhancement emission at 565 nm for pyrophosphate and 530 nm for alanine in polar solvent. The fluorescence titration experiments confirm 1:1 stoichiometric ratio with high-binding constant and very low limit of detection (LoD) values. Receptor I showed a highly selective and sensitive recognition to HP2O73- and to alanine over other competitive anions and amino acids. In addition, the fluorescence lifetime measurement and reversible binding study results support the practical importance of 1. (C) 2017 Elsevier B.V. All rights reserved.
引用
收藏
页码:465 / 471
页数:7
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