Diterpenoids from Isodon adenantha

被引：27
|
作者：
Jiang, B
Yang, H
Li, ML
Hou, AJ
Han, QB
Wang, SJ
Li, SH
Sun, HD [1 ]
机构：
[1] Acad Sinica, Kunming Inst Bot, State Key Lab Phytochem & Plant Resources W China, Kunming 650204, Peoples R China
[2] Kunming Med Coll, Yunnan Lab Pharmacol Nat Prod, Kunming 650031, Peoples R China
[3] Dali Med Coll, Dept Pharmacol, Dalian 671000, Yunnan, Peoples R China
来源：
JOURNAL OF NATURAL PRODUCTS | 2002年 / 65卷 / 08期
关键词：
D O I：
10.1021/np020084k
中图分类号：
Q94 [植物学];
学科分类号：
071001 ;
摘要：
Eleven new diterpenoids, adenanthins B-L (1-11), together with five known analogues, calcicolin B (12), adenanthin (13), weisiensin A (14), nervosanin (15), and forrestin C (16), were isolated from the aerial parts of Isodon adenantha The structures of 1-11 were elucidated on the basis of spectral methods, as well as the X ray crystallographic analysis of 11 Compounds 2, 5, and 14 showed significant inhibitory activities against K562 cells, with IC50 values less than 4 mug/mL, respectively.
引用
收藏
页码：1111 / 1116
页数：6
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