Driving the Morita-Baylis-Hillman Reaction to a Multicomponent Organic Transformation

被引：2
|
作者：
Guillouzic, Anne-Francoise [1 ]
Montel, Sonia [1 ]
Laborde, Coralie [1 ]
Volle, Jean-Noel [1 ]
Pirat, Jean-Luc [1 ]
Virieux, David [1 ]
机构：
[1] Ecole Natl Super Chim Montpellier, Inst Charles Gerhardt, UMR 5253, F-34296 Montpellier 5, France
来源：
EUROPEAN JOURNAL OF ORGANIC CHEMISTRY | 2014年 / 2014卷 / 04期
关键词：
Multicomponent reactions; Domino reactions; Phosphorus; Alkenes; Aldehydes; STEREOSELECTIVE-SYNTHESIS; HYDROPHOSPHONYLATION; PRODUCT; SUBSTITUTION; PHOSPHONATES; CARBONATES; CHEMISTRY; ALKENES; ALKYNES; ACCESS;
D O I：
10.1002/ejoc.201301226
中图分类号：
O62 [有机化学];
学科分类号：
070303 ; 081704 ;
摘要：
The combination of a trivalent phosphorus reagent with an aldehyde and a Michael olefin in the presence of water led to the formation of functionalized phosphine oxides. This approach turned the Lewis base organocatalyzed Morita-Baylis-Hillman reaction into a multicomponent organic transformation to provide rapid access to polyfunctionalized molecules.
引用
收藏
页码：788 / 796
页数：9
相关论文
共 50 条
  • [1] Sila Morita-Baylis-Hillman reaction of cyclopropenes
    Chuprakov, Stepan
    Malyshev, Denis A.
    Trofimov, Alexander
    Gevorgyan, Vladimir
    JOURNAL OF THE AMERICAN CHEMICAL SOCIETY, 2007, 129 (48) : 14868 - 14869
  • [2] Nicholas cations in the Morita-Baylis-Hillman reaction
    Campbell, Mark
    Krafft, Marie E.
    Kerrigan, Sean
    ABSTRACTS OF PAPERS OF THE AMERICAN CHEMICAL SOCIETY, 2006, 231
  • [3] Recent extensions of the Morita-Baylis-Hillman reaction
    Ma, Guang-Ning
    Jiang, Jia-Jun
    Shi, Min
    Wei, Yin
    CHEMICAL COMMUNICATIONS, 2009, (37) : 5496 - 5514
  • [4] The Morita-Baylis-Hillman reaction in aqueous-organic solvent system
    de Souza, Rodrigo O. M. A.
    Pereira, Vera L. P.
    Esteves, Pierre M.
    Vasconcellos, Mario L. A. A.
    TETRAHEDRON LETTERS, 2008, 49 (41) : 5902 - 5905
  • [5] Asymmetric organocatalytic Morita-Baylis-Hillman reaction and asymmetric organocatalytic transformations of Morita-Baylis-Hillman adducts. An update
    Pellissier, Helene
    TETRAHEDRON, 2025, 172
  • [6] Privileged chiral catalysts in asymmetric Morita-Baylis-Hillman/aza-Morita-Baylis-Hillman reaction
    Wei Yin
    Shi Min
    CHINESE SCIENCE BULLETIN, 2010, 55 (17): : 1699 - 1711
  • [7] Toward the development of an asymmetric Morita-Baylis-Hillman reaction
    Lin, YM
    Boucau, J
    ABSTRACTS OF PAPERS OF THE AMERICAN CHEMICAL SOCIETY, 2005, 230 : U3441 - U3441
  • [8] Ionic Thiourea Organocatalysis of the Morita-Baylis-Hillman Reaction
    McGrath, Trevor
    Robertson, Katherine N.
    Masuda, Jason D.
    Clyburne, Jason A. C.
    Singer, Robert D.
    AUSTRALIAN JOURNAL OF CHEMISTRY, 2016, 69 (07) : 759 - 762
  • [9] Catalytic Enantioselective Transannular Morita-Baylis-Hillman Reaction
    Mato, Raquel
    Manzano, Ruben
    Reyes, Efraim
    Carrillo, Luisa
    Uria, Uxue
    Vicario, Jose L.
    JOURNAL OF THE AMERICAN CHEMICAL SOCIETY, 2019, 141 (24) : 9495 - 9499
  • [10] Asymmetric Morita-Baylis-Hillman reaction of chiral glyoxylates
    Bauer, T
    Tarasiuk, J
    TETRAHEDRON-ASYMMETRY, 2001, 12 (12) : 1741 - 1745
12345