Aim. Evaluation of the possibilities of a new semi-quantitative rapid test for procalcitonin in the diagnosis of multisegmental community-acquired pneumonia. Materials and methods. A one-stage comparative study involved 123 patients hospitalized in a hospital with a confirmed diagnosis of community-acquired pneumonia. The mean age of the patients was 49.5 +/- 21.0 (M +/- SD) years. On the first day of hospitalization, all patients underwent a general clinical examination, chest x-ray, and a plasma procalcitonin level was determined using a semi-quantitative rapid test. Results. Indicators of a new semi-quantitative rapid test for procalcitonin of at least 2 ng/ml are directly related to laboratory and instrumental indicators reflecting the severity of community-acquired pneumonia, namely, the severity of respiratory failure (p=0.001), respiratory rate (p=0.001), and heart rate contractions (p=0.001), systolic blood pressure (p=0.025), oxygen saturation (p=0,001), erythrocyte sedimentation rate (p=0.021), fibrinogen (p=0.003) and high CRB-65 scores (p=0.001). They are also associated with multisegmental community-acquired pneumonia (chi(2)=4.7; p=0.030) and complications of this disease, such as hydrothorax (p=0.029) and death (chi(2)=22.1; p=0.001). Conclusion. Using a new semi-quantitative rapid test for procalcitonin allows you to optimize the diagnosis of complications of community-acquired pneumonia and determine the high risk of multisegmental pneumonia.
机构:
Hosp Cochin St Vincent Paul, Dept Pediat Urgences Microbiol Stat Radiol & Bioc, F-75014 Paris, FranceHosp Cochin St Vincent Paul, Dept Pediat Urgences Microbiol Stat Radiol & Bioc, F-75014 Paris, France
Gendrel, D
Moulin, F
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Hosp Cochin St Vincent Paul, Dept Pediat Urgences Microbiol Stat Radiol & Bioc, F-75014 Paris, FranceHosp Cochin St Vincent Paul, Dept Pediat Urgences Microbiol Stat Radiol & Bioc, F-75014 Paris, France
Moulin, F
Lorrot, M
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Hosp Cochin St Vincent Paul, Dept Pediat Urgences Microbiol Stat Radiol & Bioc, F-75014 Paris, FranceHosp Cochin St Vincent Paul, Dept Pediat Urgences Microbiol Stat Radiol & Bioc, F-75014 Paris, France
Lorrot, M
Marc, E
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Hosp Cochin St Vincent Paul, Dept Pediat Urgences Microbiol Stat Radiol & Bioc, F-75014 Paris, FranceHosp Cochin St Vincent Paul, Dept Pediat Urgences Microbiol Stat Radiol & Bioc, F-75014 Paris, France
Marc, E
Guérin, S
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Hosp Cochin St Vincent Paul, Dept Pediat Urgences Microbiol Stat Radiol & Bioc, F-75014 Paris, FranceHosp Cochin St Vincent Paul, Dept Pediat Urgences Microbiol Stat Radiol & Bioc, F-75014 Paris, France
Guérin, S
Soulier, N
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Hosp Cochin St Vincent Paul, Dept Pediat Urgences Microbiol Stat Radiol & Bioc, F-75014 Paris, FranceHosp Cochin St Vincent Paul, Dept Pediat Urgences Microbiol Stat Radiol & Bioc, F-75014 Paris, France
Soulier, N
Lebon, P
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Hosp Cochin St Vincent Paul, Dept Pediat Urgences Microbiol Stat Radiol & Bioc, F-75014 Paris, FranceHosp Cochin St Vincent Paul, Dept Pediat Urgences Microbiol Stat Radiol & Bioc, F-75014 Paris, France
Lebon, P
Coste, J
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Hosp Cochin St Vincent Paul, Dept Pediat Urgences Microbiol Stat Radiol & Bioc, F-75014 Paris, FranceHosp Cochin St Vincent Paul, Dept Pediat Urgences Microbiol Stat Radiol & Bioc, F-75014 Paris, France
Coste, J
Iniguez, JL
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Hosp Cochin St Vincent Paul, Dept Pediat Urgences Microbiol Stat Radiol & Bioc, F-75014 Paris, FranceHosp Cochin St Vincent Paul, Dept Pediat Urgences Microbiol Stat Radiol & Bioc, F-75014 Paris, France
Iniguez, JL
Kalifa, G
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Hosp Cochin St Vincent Paul, Dept Pediat Urgences Microbiol Stat Radiol & Bioc, F-75014 Paris, FranceHosp Cochin St Vincent Paul, Dept Pediat Urgences Microbiol Stat Radiol & Bioc, F-75014 Paris, France
Kalifa, G
Brunet, F
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Hosp Cochin St Vincent Paul, Dept Pediat Urgences Microbiol Stat Radiol & Bioc, F-75014 Paris, FranceHosp Cochin St Vincent Paul, Dept Pediat Urgences Microbiol Stat Radiol & Bioc, F-75014 Paris, France
Brunet, F
Raymond, J
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Hosp Cochin St Vincent Paul, Dept Pediat Urgences Microbiol Stat Radiol & Bioc, F-75014 Paris, FranceHosp Cochin St Vincent Paul, Dept Pediat Urgences Microbiol Stat Radiol & Bioc, F-75014 Paris, France
机构:
Univ Pittsburgh, Dept Crit Care Med, CRISMA Lab, Pittsburgh, PA 15261 USAUniv Pittsburgh, Dept Crit Care Med, CRISMA Lab, Pittsburgh, PA 15261 USA
Huang, David T.
Weissfeld, Lisa A.
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Univ Pittsburgh, Dept Crit Care Med, CRISMA Lab, Pittsburgh, PA 15261 USA
Univ Pittsburgh, Grad Sch Publ Hlth, Dept Biostat, Pittsburgh, PA 15261 USAUniv Pittsburgh, Dept Crit Care Med, CRISMA Lab, Pittsburgh, PA 15261 USA
Weissfeld, Lisa A.
Kellum, John A.
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Univ Pittsburgh, Dept Crit Care Med, CRISMA Lab, Pittsburgh, PA 15261 USAUniv Pittsburgh, Dept Crit Care Med, CRISMA Lab, Pittsburgh, PA 15261 USA
Kellum, John A.
Yeally, Donald M.
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机构:Univ Pittsburgh, Dept Crit Care Med, CRISMA Lab, Pittsburgh, PA 15261 USA
Yeally, Donald M.
Kong, Lan
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Univ Pittsburgh, Dept Crit Care Med, CRISMA Lab, Pittsburgh, PA 15261 USA
Univ Pittsburgh, Grad Sch Publ Hlth, Dept Biostat, Pittsburgh, PA 15261 USAUniv Pittsburgh, Dept Crit Care Med, CRISMA Lab, Pittsburgh, PA 15261 USA
Kong, Lan
Martino, Michael
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Jefferson Reg Med Ctr, Dept Emergency Med, Pittsburgh, PA USAUniv Pittsburgh, Dept Crit Care Med, CRISMA Lab, Pittsburgh, PA 15261 USA
Martino, Michael
Angus, Derek C.
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Univ Pittsburgh, Dept Crit Care Med, CRISMA Lab, Pittsburgh, PA 15261 USAUniv Pittsburgh, Dept Crit Care Med, CRISMA Lab, Pittsburgh, PA 15261 USA
机构:
Vanderbilt Univ, Med Ctr, Nashville, TN 37232 USAVanderbilt Univ, Med Ctr, Nashville, TN 37232 USA
Self, Wesley H.
Balk, Robert A.
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Rush Univ, Med Ctr, Chicago, IL 60612 USAVanderbilt Univ, Med Ctr, Nashville, TN 37232 USA
Balk, Robert A.
Grijalva, Carlos G.
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Vanderbilt Univ, Med Ctr, Nashville, TN 37232 USAVanderbilt Univ, Med Ctr, Nashville, TN 37232 USA
Grijalva, Carlos G.
Williams, Derek J.
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Vanderbilt Univ, Med Ctr, Nashville, TN 37232 USAVanderbilt Univ, Med Ctr, Nashville, TN 37232 USA
Williams, Derek J.
Zhu, Yuwei
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Vanderbilt Univ, Med Ctr, Nashville, TN 37232 USAVanderbilt Univ, Med Ctr, Nashville, TN 37232 USA
Zhu, Yuwei
Anderson, Evan J.
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Emory Univ, Sch Med, Atlanta, GA USAVanderbilt Univ, Med Ctr, Nashville, TN 37232 USA
Anderson, Evan J.
Waterer, Grant W.
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Univ Western Australia, Perth, WA, Australia
Northwestern Univ, Feinberg Sch Med, Chicago, IL 60611 USAVanderbilt Univ, Med Ctr, Nashville, TN 37232 USA
Waterer, Grant W.
Courtney, D. Mark
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Northwestern Univ, Feinberg Sch Med, Chicago, IL 60611 USAVanderbilt Univ, Med Ctr, Nashville, TN 37232 USA
Courtney, D. Mark
Bramley, Anna M.
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Ctr Dis Control & Prevent, Atlanta, GA USAVanderbilt Univ, Med Ctr, Nashville, TN 37232 USA
Bramley, Anna M.
Trabue, Christopher
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Univ Tennessee, Hlth Sci Ctr, St Thomas Hlth, Nashville, TN USAVanderbilt Univ, Med Ctr, Nashville, TN 37232 USA
Trabue, Christopher
Fakhran, Sherene
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John H Stroger Jr Hosp Cook Cty, Chicago, IL USAVanderbilt Univ, Med Ctr, Nashville, TN 37232 USA
Fakhran, Sherene
Blaschke, Anne J.
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Univ Utah, Sch Med, Salt Lake City, UT USAVanderbilt Univ, Med Ctr, Nashville, TN 37232 USA
Blaschke, Anne J.
Jain, Seema
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Ctr Dis Control & Prevent, Atlanta, GA USAVanderbilt Univ, Med Ctr, Nashville, TN 37232 USA
Jain, Seema
Edwards, Kathryn M.
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Vanderbilt Univ, Med Ctr, Nashville, TN 37232 USAVanderbilt Univ, Med Ctr, Nashville, TN 37232 USA
Edwards, Kathryn M.
Wunderink, Richard G.
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Northwestern Univ, Feinberg Sch Med, Chicago, IL 60611 USAVanderbilt Univ, Med Ctr, Nashville, TN 37232 USA