RTA 301 (peloruside): a novel microtubule stabilizer with potent vivo activity against lung cancer and resistant breast cancer

被引:9
|
作者
Meyer, C.
Ferguson, D.
Krauth, M.
Wick, M.
Northcote, P.
机构
[1] Reata Pharmaceut Inc, Dallas, TX USA
[2] CTRC Inst Drug Dev, San Antonio, TX USA
[3] Univ Victoria, Wellington, New Zealand
来源
EJC SUPPLEMENTS | 2006年 / 4卷 / 12期
关键词
D O I
10.1016/S1359-6349(06)70644-9
中图分类号
R73 [肿瘤学];
学科分类号
100214 ;
摘要
639
引用
收藏
页码:192 / 193
页数:2
相关论文
共 50 条
  • [21] A novel oral indoline-sulfonamide derivative, J30, exhibits potent activity against human cancer cells both in in vitro and in vivo through disruption of microtubule
    Chang, Jang-Yang
    Liou, Jing-Ping
    DRUGS OF THE FUTURE, 2007, 32 : 35 - 36
  • [22] A novel RET inhibitor with potent efficacy against medullary thyroid cancer in vivo DISCUSSION
    Weber, Collin J.
    Cohen, Mark S.
    Chen, Herb
    SURGERY, 2010, 148 (06) : 1236 - 1236
  • [23] A novel sulfonamide agent, MPSP-001, exhibits potent activity against human cancer cells in vitro through disruption of microtubule
    Liu, Zu-long
    Tian, Wei
    Wang, Yong
    Kuang, Shan
    Luo, Xiao-min
    Yu, Qiang
    ACTA PHARMACOLOGICA SINICA, 2012, 33 (02) : 261 - 270
  • [24] A novel sulfonamide agent, MPSP-001, exhibits potent activity against human cancer cells in vitro through disruption of microtubule
    Zu-long Liu
    Wei Tian
    Yong Wang
    Shan Kuang
    Xiao-min Luo
    Qiang Yu
    Acta Pharmacologica Sinica, 2012, 33 : 261 - 270
  • [25] Physapubescin B Exhibits Potent Activity against Human Prostate Cancer In Vitro and In Vivo
    Ding, Wanjing
    Hu, Zhijuan
    Zhang, Zhewen
    Ma, Qiaoqiao
    Tang, Huifang
    Ma, Zhongjun
    JOURNAL OF AGRICULTURAL AND FOOD CHEMISTRY, 2015, 63 (43) : 9504 - 9512
  • [26] BIA-6: A NOVEL AKT INHIBITOR WITH POTENT ACTIVITY IN LUNG CANCER
    Dinavahi, Saketh S.
    Alokam, Reshma
    Viswanadha, Srikant
    Dharmarajan, Sriram
    Perumal, Yogeeswari
    JOURNAL OF THORACIC ONCOLOGY, 2013, 8 : S567 - S567
  • [27] Potent in vivo antineoplastic activity of MCR peptides MCR-4 and MCR-14 against chemotherapy-resistant human small cell lung cancer
    Radulescu, RT
    Jaques, G
    DRUGS UNDER EXPERIMENTAL AND CLINICAL RESEARCH, 2003, 29 (02) : 69 - 74
  • [28] Novel indolizino[8,7-b]indole hybrids with potent activity against small cell lung cancer
    Chang, Sue-Ming
    Wu, Ming-Hsi
    Pidugu, Hima Bindu
    Su, Tsann-Long
    Lee, Te-Chang
    CANCER RESEARCH, 2017, 77
  • [29] Identifying novel and potent inhibitors of EGFR protein for the drug development against the breast cancer
    Siddiqui, Arif Jamal
    Jahan, Sadaf
    Patel, Mitesh
    Abdelgadir, Abdelmushin
    Alturaiki, Wael
    Bardakci, Fevzi
    Sachidanandan, Manojkumar
    Badraoui, Riadh
    Snoussi, Mejdi
    Adnan, Mohd
    JOURNAL OF BIOMOLECULAR STRUCTURE & DYNAMICS, 2023, 41 (23): : 14460 - 14472
  • [30] Discovery of novel steroidal-chalcone hybrids with potent and selective activity against triple-negative breast cancer
    Hou, Qiangqiang
    Lin, Xin
    Lu, Xiang
    Bai, Chengfeng
    Wei, Hanlin
    Luo, Guoshun
    Xiang, Hua
    BIOORGANIC & MEDICINAL CHEMISTRY, 2020, 28 (23)