A pilot randomized controlled study on the effect of laser photocoagulation of confluent soft macular drusen

被引：62
|
作者：
Little, HL
Showman, JM
Brown, BW
机构：
[1] ZWENG MEM RETINAL RES FDN, MENLO PK, CA 94025 USA
[2] STANFORD UNIV, SCH MED, DEPT OPHTHALMOL, STANFORD, CA 94305 USA
[3] STANFORD UNIV, DEPT HLTH RES & POLICY, STANFORD, CA 94305 USA
来源：
OPHTHALMOLOGY | 1997年 / 104卷 / 04期
关键词：
D O I：
10.1016/S0161-6420(97)30261-9
中图分类号：
R77 [眼科学];
学科分类号：
100212 ;
摘要：
Purpose: The authors determined the effect of photocoagulation of drusen on visual acuity and progression to subretinal neovascular membranes (SRNV). Methods: One of paired eyes was randomized to photocoagulation with other eye to control in 27 patients having symmetrical maculopathy and visual acuities, aged 46 to 81 years (mean, 69.7 years); follow-up 1 to 6 years (mean, 3.2 years). Results: Final visual acuity was improved in treated eye or decreased in control eye in 12 patients, equal in 13 patients, and decreased in treated eye in 2 patients (P < 0.006). Progression to SRNV was less with treatment. Conclusion: Laser photocoagulation of confluent soft macular drusen may improve long-term visual prognosis.
引用
收藏
页码：623 / 631
页数：9
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