Functional yogurt aims to protect against the aflatoxin B1 toxicity in rats

被引:22
|
作者
Abdel-Salam, Ahmed M. [1 ]
Badr, Ahmed Noah [2 ]
Zaghloul, Ahmed H. [1 ]
Farrag, Abdel Razik H. [3 ]
机构
[1] Natl Res Ctr, Dept Dairy Sci, Cairo, Egypt
[2] Natl Res Ctr, Food Toxicol & Contaminants Dept, Cairo 12622, Egypt
[3] Natl Res Ctr, Dept Pathol, Cairo, Egypt
关键词
Aflatoxin; Chicory-root extract; Functional yogurt; Mycotoxin; Oxidative stress; PROBIOTICS LACTOBACILLUS-RHAMNOSUS; DAIRY-PRODUCTS; BIFIDOBACTERIUM-LACTIS; INULIN; SUPPLEMENTATION; METABOLISM; ASSAY; MILK; B-1; OLIGOSACCHARIDES;
D O I
10.1016/j.toxrep.2020.10.012
中图分类号
R99 [毒物学(毒理学)];
学科分类号
100405 ;
摘要
Recently, the rise of mycotoxin contamination in food materials was found to be due to several factors, including climatic changes' impact. Therefore, the aim of this study was to provide a novel food product that allows the reduction of aflatoxin impact in animal tissues. Chicory root-extract (CRE) was evaluated for its active components, antioxidant potency, and antimicrobial activity. The CRE was utilized to produce functional yogurt (FY) that was evaluated in-vivo using experimental rats. The CRE showed high antioxidant activity and recorded valuable content of the active components. Results also showed a high antimicrobial effect against toxigenic fungal strains. The results have reflected the efficiency of the FY to suppress aflatoxin impacts in the animal tissues and biochemical parameters of rats-serum. An enhancement was recorded inliver and kidney functions for rats taking FY with the presence of aflatoxin. It was concluded that consumption of the FY assisted in suppression of the oxidative stress in rats-tissues.
引用
收藏
页码:1412 / 1420
页数:9
相关论文
共 50 条
  • [31] Antagonistic role of barley against bioaccumulation and oxidative stress of aflatoxin B1 in male rats
    Elgohary, Mohamed Ramadan
    Abdel-Fattah, Shaaban Mostafa
    Abu-Sree, Yehia Hassan
    Morsy, Gamal Mohamed
    Ali, Atef Abdel-Moneem
    JOURNAL OF BASIC AND APPLIED ZOOLOGY, 2022, 83 (01):
  • [32] ABILITY OF LACTOBACILLUS CASEI AND LACTOBACILLUS ACIDOPHILUS TO PROTECT AGANIST THE TOXICITY IN BROILERS FED CONTAMINATED DIET AFLATOXIN B1
    Shlej, A. A.
    Saaid, J. M.
    Thlij, K. M.
    IRAQI JOURNAL OF AGRICULTURAL SCIENCES, 2015, 46 (04): : 652 - 661
  • [33] Protective and Therapeutic Effects of Lactic Acid Bacteria against Aflatoxin B1 Toxicity to Rat Organs
    Ashi, Hayat
    Almalki, Meshal H. K.
    Hamed, Enas A.
    Ramadan, Wafaa S.
    Alahmadi, Tahani F. H.
    Alami, Outour Tariq
    Arafa, Sara H.
    Alshareef, Atheer K.
    Alsulami, Fatimah S.
    Alharbi, Areej F.
    Al-Harbi, Manahil S.
    Alqurashi, Ebtehal H.
    Aashi, Shirin
    Alzahrani, Youssef A.
    Elbanna, Khaled
    Abulreesh, Hussein H.
    MICROORGANISMS, 2023, 11 (07)
  • [34] Algal extracts evaluation as an Antitoxicity sustainable solution against aflatoxin B1 toxicity in rat tissues
    Marrez, Diaa Attia
    Badr, Ahmed Noah
    El-Bahrawy, Amanallah
    Naeem, Mohamed Ahmed
    TOXICON, 2024, 250
  • [35] Functional role of selenium-fortified yogurt against aflatoxin-contaminated nuts in rats
    Alsuhaibani A.M.A.
    Agriculture & Food Security, 7 (1):
  • [36] Omics analysis revealed the intestinal toxicity induced by aflatoxin B1 and aflatoxin M1
    Gao, Ya-Nan
    Wang, Zi-Wei
    Su, Chuan-You
    Wang, Jia-Qi
    Zheng, Nan
    ECOTOXICOLOGY AND ENVIRONMENTAL SAFETY, 2024, 278
  • [37] Effects of bicyclol on aflatoxin B1 metabolism and hepatotoxicity in rats
    Lu, H
    Li, Y
    ACTA PHARMACOLOGICA SINICA, 2002, 23 (10) : 942 - 945
  • [38] TERATOGENIC RESPONSE BY HAMSTERS RATS AND MICE TO AFLATOXIN B1
    DIPAOLO, JA
    ELIS, J
    ERWIN, H
    NATURE, 1967, 215 (5101) : 638 - +
  • [39] Screening of Aptamers for Aflatoxin B1 and Establishment of a Method for Aflatoxin B1 Detection
    Zhang M.
    Zhang X.
    Li C.
    Gao H.
    Liu J.
    Tian Y.
    Ma W.
    Li Y.
    Tan J.
    Shipin Kexue/Food Science, 2020, 41 (24): : 295 - 303
  • [40] AFLATOXIN B1 CARCINOGENESIS IN LIPOTROPE-DEFICIENT RATS
    ROGERS, AE
    NEWBERNE, PM
    CANCER RESEARCH, 1969, 29 (11) : 1965 - &