Instructable Nanoparticles Using Dynamic Combinatorial Chemistry

被引：16

作者：

Han, Yang ^{[1
]}

Nowak, Piotr ^{[1
]}

Colomb-Delsuc, Mathieu ^{[1
]}

Leal, Manuel Pernia ^{[1
]}

Otto, Sijbren ^{[1
]}

机构：

[1] Univ Groningen, Ctr Syst Chem, Stratingh Inst, NL-9747 AG Groningen, Netherlands

来源：

LANGMUIR | 2015年 / 31卷 / 46期

关键词：

SELF-ASSEMBLED MONOLAYERS; NUCLEOPHILIC CATALYSIS; COVALENT CHEMISTRY; GOLD; RECOGNITION; LIBRARIES; SURFACE; EQUILIBRATION; RECEPTOR; FUNCTIONALIZATION;

D O I：

10.1021/acs.langmuir.5b03673

中图分类号：

O6 [化学];

学科分类号：

0703 ;

摘要：

The application of nanoparticles to the multivalent recognition of biomacromolecules or programmed self-assembly requires control over the relative placement of chemical groups on their surface. We have developed a method to direct the functionalization of surfaces of aldehyde-equipped gold nanoparticles using a DNA template. An error-correction mechanism is built into the functionalization process thanks to the thermodynamic control enabled by the hydrazone exchange reaction. This reversible reaction can be conveniently switched off by removing the catalyst, preserving the functionalization.

引用

页码：12658 / 12663

页数：6

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