Randomized Controlled Trials in Pancreatic Surgery - an Update

This review provides a summary of important, completed and published clinical trials, together with interesting and important running RCTs in pancreatic surgery. Randomised controlled studies (RCT) are one of the most important sources of new evidence for the treatment of cancer patients. This is particularly the case for pancreas surgery, where complications are comparatively common and serious and innovative surgical techniques and peri-interventional innovations are needed that could reduce morbidity and mortality. Although there are many very different methodological challenges in performing surgical RCTs, large surgical RCTs of high scientific quality have been completed during the last 10 years.