Hirsutellone F, a dimer of antitubercular alkaloids from the seed fungus Trichoderma species BCC 7579

被引：88

作者：

Isaka, Masahiko ^{[1
]}

Prathumpai, Wai ^{[1
]}

Wongsa, Patcharaporn ^{[1
]}

Tanticharoen, Morakot ^{[1
]}

机构：

[1] Natl Ctr Genet Engn & Biotechnol, BIOTEC, Pathum Thani 12120, Thailand

来源：

ORGANIC LETTERS | 2006年 / 8卷 / 13期

关键词：

D O I：

10.1021/ol060926x

中图分类号：

O62 [有机化学];

学科分类号：

070303 ; 081704 ;

摘要：

Hirsutellone F (7), a novel alkaloid dimer, was isolated together with known monomers, hirsutellones A (1), B (2), and C (3), from the seed fungus Trichoderma sp. BCC 7579. The structure of 7 was elucidated by spectroscopic analysis. Studies on biomimetic chemistry, using the dimer 7, suggested that compound 8 (17,1'-dehydrohirsutellone B) should be the precursor for all hirsutellones.

引用

页码：2815 / 2817

页数：3

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