Pregnancy and Catastrophic Antiphospholipid Syndrome

被引:20
|
作者
Gomez-Puerta, Jose A. [1 ]
Sanin-Blair, Jose [2 ]
Galarza-Maldonado, Claudio [3 ]
机构
[1] Hosp Clin Barcelona, Dept Rheumatol, E-08036 Barcelona, Spain
[2] Univ Pontificia Bolivariana, Grp GIE SHAE, Maternal Fetal Med Unit, Medellin, Colombia
[3] Hosp Monte Sinai, UNERA, Rheumat & Autoimmune Dis Unit, Cuenca, Ecuador
关键词
Antiphospholipid syndrome; Catastrophic antiphospholipid syndrome; HELLP syndrome; Pre-eclampsia; SYSTEMIC-LUPUS-ERYTHEMATOSUS; ELEVATED LIVER-ENZYMES; HELLP-SYNDROME; ANTIBODIES; MANAGEMENT; DIAGNOSIS; AUTOIMMUNITY; CONTROVERSIES; PREECLAMPSIA; PATHOGENESIS;
D O I
10.1007/s12016-008-8100-3
中图分类号
R392 [医学免疫学];
学科分类号
100102 ;
摘要
Antiphospholipid syndrome (APS) is clearly related to maternal morbidity. The most characteristic feature is pregnancy loss; however, several other serious complications had been reported including fetal growth restriction, uteroplacental insufficiency, fetal distress, pre-eclampsia, and HELLP syndrome. Herein, we review the different aspects of obstetric APS features, with special emphasis on its life-threatening variant known as catastrophic APS (Asherson's syndrome) and its relationship with a thrombotic microangiopathy such as HELLP syndrome.
引用
收藏
页码:85 / 90
页数:6
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