Catastrophic Antiphospholipid Syndrome Diagnosis and Management in Pregnancy

被引：20
|
作者：
Gomez-Puerta, Jose A. [1 ,2 ]
Espinosa, Gerard [1 ]
Cervera, Ricard [1 ]
机构：
[1] Hosp Clin Barcelona, Dept Autoimmune Dis, E-08036 Barcelona, Catalonia, Spain
[2] Brigham & Womens Hosp, Clin Sci Sect, Div Rheumatol Allergy & Immunol, Boston, MA 02115 USA
来源：
CLINICS IN LABORATORY MEDICINE | 2013年 / 33卷 / 02期
关键词：
Antiphospholipid syndrome; Antiphospholipid antibodies; Catastrophic antiphospholipid syndrome; Pregnancy; Puerperium; Thrombosis; VENOUS THROMBOEMBOLISM; CLASSIFICATION; PUERPERIUM; CRITERIA;
D O I：
10.1016/j.cll.2013.01.003
中图分类号：
R446 [实验室诊断]; R-33 [实验医学、医学实验];
学科分类号：
1001 ;
摘要：
Catastrophic antiphospholipid syndrome (CAPS) is a potentially lethal variant of antiphospholipid syndrome, characterized by multiorgan thrombosis in a short period of time, affecting mainly small vessels. In approximately 50% of CAPS cases, the catastrophic event is preceded by a trigger, mainly infections, or surgery, anticoagulation withdrawal, lupus flares, neoplasm, or pregnancy and puerperium. Treatment of CAPS is based on expert opinion and relies on a combination of several strategies, including anticoagulation, steroids, plasma exchange sessions, and/or intravenous immunoglobulins.
引用
收藏
页码：391 / +
页数：11
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