One- and Two-Photon Turn-on Fluorescent Probe for Cysteine and Homocysteine with Large Emission Shift

被引：155
|
作者：
Zhang, Xuanjun [1 ]
Ren, Xinsheng [1 ]
Xu, Qing-Hua [1 ]
Loh, Kian Ping [1 ]
Chen, Zhi-Kuan [2 ]
机构：
[1] Natl Univ Singapore, Dept Chem, Singapore 117543, Singapore
[2] Inst Mat Res & Engn, Singapore 117602, Singapore
来源：
ORGANIC LETTERS | 2009年 / 11卷 / 06期
关键词：
CHEMOSENSOR; DENDRIMERS;
D O I：
10.1021/ol802979n
中图分类号：
O62 [有机化学];
学科分类号：
070303 ; 081704 ;
摘要：
A novel dendritic chromophore with efficient intramolecular charge transfer (ICT) and strong two-photon absorption (TPA) was designed as a turn-on fluorescent probe for cysteine (Cys) and homocysteine (Hcy). The probe exhibited greatly enhanced fluorescence intensity as well as a very large emission peak shift (165 nm) upon addition of Cys/Hcy due to ICT switch off. The sensing process was also monitored by two-photon excited fluorescence (TPEF).
引用
收藏
页码：1257 / 1260
页数：4
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