Polyester Dendrimers: Smart Carriers for Drug Delivery

被引：61
|
作者：
Twibanire, Jean-d'Amour K. [1 ,2 ]
Grindley, T. Bruce [1 ]
机构：
[1] Dalhousie Univ, Dept Chem, Halifax, NS B3H 4R2, Canada
[2] CanAm Bioresearch Inc, Winnipeg, MB R3T 0P4, Canada
来源：
POLYMERS | 2014年 / 6卷 / 01期
基金：
加拿大自然科学与工程研究理事会;
关键词：
polyester dendrimers; biocompatibility; drug delivery; smart carriers; drug delivery pathways; polymersomes; BLOCK-COPOLYMER MICELLES; NEUTRON-CAPTURE THERAPY; IN-VIVO EVALUATION; TUNABLE MOLECULAR-WEIGHT; CROSS-LINKED MICELLES; MRI CONTRAST AGENTS; BOW-TIE HYBRIDS; ORAL DELIVERY; MACROMOLECULAR THERAPEUTICS; POLY(AMIDOAMINE) DENDRIMERS;
D O I：
10.3390/polym6010179
中图分类号：
O63 [高分子化学（高聚物）];
学科分类号：
070305 ; 080501 ; 081704 ;
摘要：
Polyester dendrimers have been shown to be outstanding candidates for biomedical applications. Compared to traditional polymeric drug vehicles, these biodegradable dendrimers show excellent advantages especially as drug delivery systems because they are non-toxic. Here, advances on polyester dendrimers as smart carriers for drug delivery applications have been surveyed. Both covalent and non-covalent incorporation of drugs are discussed.
引用
收藏
页码：179 / 213
页数：35
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