Bioactive oligomers from natural polyhydroxyalkanoates and their synthetic analogues

被引：8
|
作者：
Adamus, Grazyna [1 ]
Kurcok, Piotr [1 ]
Radecka, Iza [2 ]
Kowalczuk, Marek [1 ,2 ]
机构：
[1] Polish Acad Sci, Ctr Polymer & Carbon Mat, 34 M Curie Sklodowskiej St, PL-41119 Zabrze, Poland
[2] Wolverhampton Univ, Fac Sci & Engn, Sch Biol Chem & Forens Sci, Wolverhampton WV1 1LY, England
来源：
POLIMERY | 2017年 / 62卷 / 04期
关键词：
aliphatic polyester; anionic polymerization; bioactive oligomer; beta-substituted beta-lactone; RING-OPENING POLYMERIZATION; RACEMIC-BETA-BUTYROLACTONE; MOLECULAR-LEVEL STRUCTURE; ANIONIC-POLYMERIZATION; STRUCTURAL-CHARACTERIZATION; MASS-SPECTROMETRY; DELIVERY-SYSTEMS; DEGRADATION; ACID; PHB;
D O I：
10.14314/polimery.2017.317
中图分类号：
O63 [高分子化学（高聚物）];
学科分类号：
070305 ; 080501 ; 081704 ;
摘要：
Contemporary reports on the bioactive oligomers derived from natural aliphatic co-polyesters (PHA) and their synthetic analogues, formed through anionic ring-opening polymerization (ROP) of beta-substituted beta-lactones are presented. Synthetic routes for such oligomers, developed mostly by Polish authors, are discussed. The described approaches enable design of novel biodegradable and bioactive oligomers for diverse applications in medicine, cosmetic industry and agrochemistry.
引用
收藏
页码：317 / 322
页数：6
相关论文
共 50 条
  • [31] Phenazine natural products: Biosynthesis, synthetic analogues, and biological activity
    Laursen, JB
    Nielsen, J
    CHEMICAL REVIEWS, 2004, 104 (03) : 1663 - 1685
  • [32] Natural α-conotoxins and their synthetic analogues in study of nicotinic acetylcholine receptors
    I. E. Kasheverov
    Yu. N. Utkin
    V. I. Tsetlin
    Russian Journal of Bioorganic Chemistry, 2006, 32 : 103 - 115
  • [33] Natural abenquines and synthetic analogues: Preliminary exploration of their cytotoxic activity
    Nain-Perez, Amalyn
    Barbosa, Luiz C. A.
    Rodriguez-Hernandez, Diego
    Kramell, Annemarie E.
    Heller, Lucie
    Csuk, Rene
    BIOORGANIC & MEDICINAL CHEMISTRY LETTERS, 2017, 27 (05) : 1141 - 1144
  • [34] The comparative toxicity to soil invertebrates of natural chemicals and their synthetic analogues
    Whitaker, J.
    Chaplow, J. S.
    Potter, E.
    Scott, W. A.
    Hopkin, S.
    Harman, M.
    Sims, I.
    Sorokin, N.
    CHEMOSPHERE, 2009, 76 (03) : 345 - 352
  • [35] Natural α-conotoxins and their synthetic analogues in study of nicotinic acetylcholine receptors
    Kasheverov, I. E.
    Min, Yu. N.
    Tsetlin, V. I.
    RUSSIAN JOURNAL OF BIOORGANIC CHEMISTRY, 2006, 32 (02) : 103 - 115
  • [36] Recent Trends in the Antidiabetic Prominence of Natural and Synthetic Analogues of Aurones
    Aluru, Rammohan
    Mukherjee, Anindita
    Zyryanov, Grigory V.
    Majee, Adinath
    Santra, Sougata
    CURRENT ISSUES IN MOLECULAR BIOLOGY, 2023, 45 (10) : 8461 - 8475
  • [37] Simple, tunable synthetic routes to cannabinoid natural product analogues
    Navaratne, Primali
    Grenning, Alexander
    ABSTRACTS OF PAPERS OF THE AMERICAN CHEMICAL SOCIETY, 2019, 257
  • [38] Synthetic investigations towards polypeptide natural products and xenortide analogues
    Wickman, Malachi
    Beecher, Jacob
    Leggans, Erick
    ABSTRACTS OF PAPERS OF THE AMERICAN CHEMICAL SOCIETY, 2016, 251
  • [39] A natural flavonoid and synthetic analogues protect the gastric mucosa from aspirin-induced erosions
    Lewis, DA
    Shaw, GP
    JOURNAL OF NUTRITIONAL BIOCHEMISTRY, 2001, 12 (02): : 95 - 100
  • [40] A SYNTHETIC APPROACH TO THE BIOACTIVE POLYENE NATURAL PRODUCT LEUCETTAMOL-A
    URBERG, S
    MCDONALD, AI
    LEAHY, JW
    ABSTRACTS OF PAPERS OF THE AMERICAN CHEMICAL SOCIETY, 1994, 207 : 369 - ORGN
12345