Mistletoe lectins and radiation-induced micronuclei in human lymphocytes

被引：0
|
作者：
Köteles, GJ [1 ]
Kubasova, T [1 ]
Horváth, G [1 ]
Pfüller, U [1 ]
机构：
[1] Frederic Joliot Curie Natl Res Inst Radiobiol & R, H-1775 Budapest, Hungary
来源：
EFFECTS OF ANTINUTRIENTS ON THE NUTRITIONAL VALUE OF LEGUME DIETS, VOL 6 | 1999年
关键词：
D O I：
暂无
中图分类号：
TS2 [食品工业];
学科分类号：
0832 ;
摘要：
Cytotoxic concentrations of mistletoe isolectins (ML-I, ML-II, ML-III) in various cell biological tests were determined. Slight clastogenic effects of the lectins were found at or above 10(-9) g/ml concentrations. The radiation-damage carrying cytokinesis-blocked (CB) cells proved to be more sensitive upon mistletoe treatment than the undamaged ones as detected through the disappearances of radiation-induced micronuclei both in cultures in vitro and in rabbits, in vivo.
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页码：134 / 138
页数：5
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