Optimal designs for regression models with forced measurements at baseline

被引：0
|
作者：
Fedorov, VV [1 ]
Leonov, S [1 ]
机构：
[1] GlaxoSmithKline, Collegeville, PA 19426 USA
来源：
MODA 7 - ADVANCES IN MODEL-ORIENTED DESIGN AND ANALYSIS, PROCEEDINGS | 2004年
关键词：
locally optimal designs; random effects; baseline; placebo effect; multiple measurements per patient;
D O I：
暂无
中图分类号：
O21 [概率论与数理统计]; C8 [统计学];
学科分类号：
020208 ; 070103 ; 0714 ;
摘要：
We discuss the construction of D-optimal designs for regression models with forced measurements. Such models may be used in dose response studies where a baseline measurement is taken for all patients, that is forced in the design.
引用
收藏
页码：61 / 69
页数：9
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