Optimal designs for regression models with forced measurements at baseline

被引：0

作者：

Fedorov, VV ^{[1
]}

Leonov, S ^{[1
]}

机构：

[1] GlaxoSmithKline, Collegeville, PA 19426 USA

来源：

MODA 7 - ADVANCES IN MODEL-ORIENTED DESIGN AND ANALYSIS, PROCEEDINGS | 2004年

关键词：

locally optimal designs; random effects; baseline; placebo effect; multiple measurements per patient;

D O I：

暂无

中图分类号：

O21 [概率论与数理统计]; C8 [统计学];

学科分类号：

020208 ; 070103 ; 0714 ;

摘要：

We discuss the construction of D-optimal designs for regression models with forced measurements. Such models may be used in dose response studies where a baseline measurement is taken for all patients, that is forced in the design.

引用

页码：61 / 69

页数：9

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