Network meta-analysis for indirect treatment comparisons

被引：863
|
作者：
Lumley, T [1 ]
机构：
[1] Univ Washington, Dept Biostat, Seattle, WA 98195 USA
来源：
STATISTICS IN MEDICINE | 2002年 / 21卷 / 16期
关键词：
meta-analysis; mixed model; random effects model; controlled trial;
D O I：
10.1002/sim.1201
中图分类号：
Q [生物科学];
学科分类号：
07 ; 0710 ; 09 ;
摘要：
I present methods for assessing the relative effectiveness of two treatments when they have not been compared directly in a randomized trial but have each been compared to other treatments. These network meta-analysis techniques allow estimation of both heterogeneity in the effect of any given treatment and inconsistency ('incoherence') in the evidence from different pairs of treatments. A simple estimation procedure using linear mixed models is given and used in a meta-analysis of treatments for acute myocardial infarction. Copyright (C) 2002 John Wiley Sons, Ltd.
引用
收藏
页码：2313 / 2324
页数：12
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