Asymmetric synthesis .41. Totally stereoselective synthesis of 1,3-disubstituted tetrahydroisoquinolines via the CN(R,S) method.

被引：22

作者：

Gosmann, G ^{[1
]}

Guillaume, D ^{[1
]}

Husson, HP ^{[1
]}

机构：

[1] UNIV PARIS 05,CHIM THERAPEUT LAB,CNRS,FAC SCI PHARMACEUT & BIOL,F-75270 PARIS 06,FRANCE

来源：

TETRAHEDRON LETTERS | 1996年 / 37卷 / 25期

关键词：

D O I：

10.1016/0040-4039(96)00819-2

中图分类号：

O62 [有机化学];

学科分类号：

070303 ; 081704 ;

摘要：

Optically active cis- or trans-1,3-disubstituted tetrahydroisoquinolines can be prepared selectively from the same oxazolidine 4. This latter is easily obtained from keto-acid 1 and (R)-(-)phenylglycinol. Copyright (C) 1996 Elsevier Science Ltd

引用

页码：4369 / 4372

页数：4

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