Asymmetric synthesis .41. Totally stereoselective synthesis of 1,3-disubstituted tetrahydroisoquinolines via the CN(R,S) method.

被引：22
|
作者：
Gosmann, G [1 ]
Guillaume, D [1 ]
Husson, HP [1 ]
机构：
[1] UNIV PARIS 05,CHIM THERAPEUT LAB,CNRS,FAC SCI PHARMACEUT & BIOL,F-75270 PARIS 06,FRANCE
来源：
TETRAHEDRON LETTERS | 1996年 / 37卷 / 25期
关键词：
D O I：
10.1016/0040-4039(96)00819-2
中图分类号：
O62 [有机化学];
学科分类号：
070303 ; 081704 ;
摘要：
Optically active cis- or trans-1,3-disubstituted tetrahydroisoquinolines can be prepared selectively from the same oxazolidine 4. This latter is easily obtained from keto-acid 1 and (R)-(-)phenylglycinol. Copyright (C) 1996 Elsevier Science Ltd
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收藏
页码：4369 / 4372
页数：4
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