Can cardiac resynchronization therapy be used as a tool to reduce sudden cardiac arrest risk?

被引：0

作者：

Galand, Vincent ^{[1
,2
]}

Singh, Jagmeet P. ^{[2
]}

Heist, E. Kevin ^{[2
]}

机构：

[1] Univ Rennes, CHU Rennes, INSERM, LTSI,UMR 1099, F-35000 Rennes, France

[2] Harvard Med Sch, Massachusetts Gen Hosp, Cardiol Div, 55 Fruit St, Boston, MA 02114 USA

来源：

PROGRESS IN CARDIOVASCULAR DISEASES | 2019年 / 62卷 / 03期

关键词：

Cardiac resynchronization therapy; Sudden cardiac arrest; Ventricular arrhythmias; IMPLANTABLE CARDIOVERTER-DEFIBRILLATOR; VENTRICULAR EJECTION FRACTION; MYOCARDIAL GENE-EXPRESSION; HEART-FAILURE; TRANSMURAL DISPERSION; PRIMARY PREVENTION; SUPER-RESPONDERS; QT INTERVAL; ARRHYTHMIAS; OUTCOMES;

D O I：

10.1016/j.pcad.2019.04.004

中图分类号：

R5 [内科学];

学科分类号：

1002 ; 100201 ;

摘要：

Patients with cardiomyopathy and reduced left ventricular (LV) ejection fraction are at risk of heart failure (HF) symptoms and sudden cardiac arrest (SCA). In selected HF patients, cardiac resynchronization therapy (CRT) provides LV reverse remodeling and improves the cellular and molecular function. However controversial results have been published regarding the effect of CRT on the residual ventricular arrhythmia risk. Indeed, the decrease in SCA risk is inconsistent and some factors strongly influence the residual post implantation arrhythmic risk. Conversely, proarrhythmic effect of CRT has been previously described. In this review we aim to describe the relationship between CRT implantation and the SCA risk decrease and discuss the patients who only require cardiac resynchronization therapy-pacemaker and those who need a concomitant implantable cardioverter defibrillator. (C) 2019 Published by Elsevier Inc.

引用

页码：242 / 248

页数：7

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