An Extremely Productive and Sustainable Procedure for the Synthesis of 2,4,5-Trisubstituted Imidazoles Using Graphene Oxide-Substituted Sulfoacetic Acid Amide

An extremely productive and sustainable procedure is described for the production of triaryl imidazoles in the presence of graphene oxide-substituted sulfoacetic acid amide as catalyst. Triaryl imidazoles were efficiently synthesized from substituted aromatic aldehydes, benzil, and ammonium acetate via a one-pot procedure using the prepared catalyst under solvent-free conditions. The proposed method showed several advantages over other catalysts, including cost effectiveness, feasibility, green procedure, excellent yields, and short reaction times. The catalyst can be reused for five cycles without significant reduction in its catalytic activity.