The spindle assembly checkpoint

被引：313
|
作者：
Rudner, AD
Murray, AW
机构：
[1] Department of Physiology, Box 0444, Univ. of California at San Francisco, San Francisco, CA 94143-0444
来源：
CURRENT OPINION IN CELL BIOLOGY | 1996年 / 8卷 / 06期
关键词：
D O I：
10.1016/S0955-0674(96)80077-9
中图分类号：
Q2 [细胞生物学];
学科分类号：
071009 ; 090102 ;
摘要：
The spindle assembly checkpoint monitors proper chromosome attachment to spindle microtubules and is conserved from yeast to humans. Checkpoint components reside on kinetochores of chromosomes and show changes in phosphorylation and localization as cells proceed through mitosis. Adaptation to prolonged checkpoint arrest can occur by inhibitory phosphorylation of Cdc2.
引用
收藏
页码：773 / 780
页数：8
相关论文
共 50 条
  • [31] Determinants of robustness in spindle assembly checkpoint signalling
    Stephanie Heinrich
    Eva-Maria Geissen
    Julia Kamenz
    Susanne Trautmann
    Christian Widmer
    Philipp Drewe
    Michael Knop
    Nicole Radde
    Jan Hasenauer
    Silke Hauf
    Nature Cell Biology, 2013, 15 : 1328 - 1339
  • [32] Tracing the pathway of spindle assembly checkpoint signaling
    Gillett, ES
    Sorger, PK
    DEVELOPMENTAL CELL, 2001, 1 (02) : 162 - 164
  • [33] Kinetic framework of spindle assembly checkpoint signaling
    Dick, A. E.
    Gerlich, D. W.
    MOLECULAR BIOLOGY OF THE CELL, 2013, 24
  • [34] Releasing the spindle assembly checkpoint without tension
    McEwen, Bruce F.
    Dong, Yimin
    JOURNAL OF CELL BIOLOGY, 2009, 184 (03): : 355 - 356
  • [35] Evolutionary Dynamics of the Spindle Assembly Checkpoint in Eukaryotes
    Kops, Geert J. P. L.
    Snel, Berend
    Tromer, Eelco C.
    CURRENT BIOLOGY, 2020, 30 (10) : R589 - R602
  • [36] In Vitro Studies of the Spindle Assembly Checkpoint in Yeast
    Opoku, Kwaku N.
    Asbury, Charles
    BIOPHYSICAL JOURNAL, 2014, 106 (02) : 166A - 167A
  • [37] The spindle assembly checkpoint requires phosphatase activity
    Foss, Kristen
    Zhang, Liguo
    Robeson, Alexander C.
    Kornbluth, Sally
    CANCER RESEARCH, 2015, 75
  • [38] Quantitative analysis of the spindle assembly checkpoint.
    Heinrich, S.
    Geissen, E-M.
    Kamenz, J.
    Trautmann, S.
    Knop, M.
    Radde, N.
    Hauf, S.
    MOLECULAR BIOLOGY OF THE CELL, 2011, 22
  • [39] Kinetochore stretching inactivates the spindle assembly checkpoint
    Uchida, Kazuhiko S. K.
    Takagaki, Kentaro
    Kumada, Kazuki
    Hirayama, Youko
    Noda, Tetsuo
    Hirota, Toru
    JOURNAL OF CELL BIOLOGY, 2009, 184 (03): : 383 - 390
  • [40] Determinants for robustness in spindle assembly checkpoint signaling
    Heinrich, S.
    Geissen, E-M.
    Trautmann, S.
    Kamenz, J.
    Widmer, C.
    Drewe, P.
    Knop, M.
    Radde, N.
    Hasenauer, J.
    Hauf, S.
    MOLECULAR BIOLOGY OF THE CELL, 2013, 24
12345