Identification of a novel allele, B*15012, by polymerase chain reaction using sequence-specific primers (PCR-SSP) and sequence-based typing

被引:0
|
作者
Day, S
van Dam, M
Buckland, E
Dunn, PPJ
Ross, J
机构
[1] UKTSSA, Bristol BS12 GRR, Avon, England
[2] St Marys Hosp, Brent Lab, London, England
来源
TISSUE ANTIGENS | 2000年 / 55卷 / 01期
关键词
HLA-B; HLA-B*15012; HLA-B*15011; sequence-based typing;
D O I
10.1034/j.1399-0039.2000.550116.x
中图分类号
Q2 [细胞生物学];
学科分类号
071009 ; 090102 ;
摘要
We report here a new allele, B*15012, identified by polymerase chain reaction using sequence-specific primers (PCR-SSP) and sequence-based typing (SBT), B*15012 differs to B*15011 (previously named B*1501) by a single nucleotide, at position 435 of codon 120. B*15011 encodes AAG and B*15012 encodes AAA at codon 120, this difference does not result in an amino acid change.
引用
收藏
页码:78 / 79
页数:2
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