Import of carrier proteins into mitochondria

被引：25

作者：

Truscott, KN ^{[1
]}

Pfanner, N ^{[1
]}

机构：

[1] Univ Freiburg, Inst Biochem & Mol Biol, D-79104 Freiburg, Germany

来源：

BIOLOGICAL CHEMISTRY | 1999年 / 380卷 / 10期

关键词：

AAC; mitochondrial carriers; protein import; Tim; Tom;

D O I：

10.1515/BC.1999.146

中图分类号：

Q5 [生物化学]; Q7 [分子生物学];

学科分类号：

071010 ; 081704 ;

摘要：

Carrier proteins located in the inner membrane of mitochondria are responsible for the exchange of metabolites between the intermembrane space and the matrix of this organelle. All members of this family are nuclear-encoded and depend on translocation machineries for their import into mitochondria. Recently many new translocation components responsible for the import of carrier proteins were identified. It is now possible to describe a detailed import pathway for this class of proteins. This review highlights the contribution made by translocation components to the process of carrier protein import into mitochondria.

引用

页码：1151 / 1156

页数：6

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