Merkel cell carcinoma

被引:1
|
作者
Wosnitza, M. [1 ]
Bozkurt, A. [2 ]
O'Dey, D. [2 ]
Pallua, N. [2 ]
Megahed, M. [1 ]
机构
[1] Univ Klinikum RWTH Aachen, Klin Allergol & Dermatol, D-52074 Aachen, Germany
[2] Univ Klinikum RWTH Aachen, Klin Plast Chirurg Hand & Verbrennungschirurg, D-52074 Aachen, Germany
来源
HAUTARZT | 2009年 / 60卷 / 05期
关键词
Merkel cell carcinoma; Neuroendocrine carcinoma; Polyomavirus; SKIN;
D O I
10.1007/s00105-009-1748-7
中图分类号
R75 [皮肤病学与性病学];
学科分类号
100206 ;
摘要
A 67-year old patient developed multiple flesh-colored nodules on the back of his left hand. Histological examination led to the diagnosis of a Merkel cell carcinoma (MCC). This highly aggressive primary cutaneous tumor is classified as a neuroendocrine carcinoma. It affects mostly elderly and immunosuppressed patients. Recently, a new polyomavirus (MCPyV) has been detected in about 75-85% of MCC and seems to play an important role in their pathogenesis. This new finding may help to develop new therapeutic options for MCC.
引用
收藏
页码:366 / +
页数:3
相关论文
共 50 条
  • [31] Merkel cell carcinoma
    Mann, GB
    Allen, PJ
    Coit, DG
    [J]. AUSTRALIAN AND NEW ZEALAND JOURNAL OF SURGERY, 1999, 69 (02): : 87 - 87
  • [32] Merkel cell carcinoma
    Drusio, Christina
    Becker, Juergen C.
    Schadendorf, Dirk
    Ugurel, Selma
    [J]. ONKOLOGE, 2018, 24 (12): : 1037 - 1049
  • [33] Merkel cell carcinoma
    Patel, P.
    Hussain, K.
    [J]. CLINICAL AND EXPERIMENTAL DERMATOLOGY, 2021, 46 (05) : 814 - 819
  • [34] Merkel cell polyomavirus and associated Merkel cell carcinoma
    Yang, June F.
    You, Jianxin
    [J]. TUMOUR VIRUS RESEARCH, 2022, 13
  • [35] Merkel Cell Carcinoma
    Schultz, Erwin
    [J]. LARYNGO-RHINO-OTOLOGIE, 2023, 102 (08) : 572 - 577
  • [36] Merkel cell carcinoma
    OConnor, WJ
    Brodland, DG
    [J]. DERMATOLOGIC SURGERY, 1996, 22 (03) : 262 - 267
  • [37] Merkel cell carcinoma
    Bahadir, S
    Çobanglu, Ü
    Alpay, K
    Özoran, Y
    Parlat, P
    Aykanat, D
    [J]. JOURNAL OF THE EUROPEAN ACADEMY OF DERMATOLOGY AND VENEREOLOGY, 2003, 17 (05) : 602 - 604
  • [38] Merkel cell carcinoma
    Becker, J. C.
    [J]. ANNALS OF ONCOLOGY, 2010, 21 : 81 - 85
  • [39] Merkel cell carcinoma
    Gutzmer, Ralf
    Drusio, Christina
    Becker, Jurgen C.
    Schadendorf, Dirk
    Ugurel, Selma
    [J]. ONKOLOGE, 2021, 27 (06): : 569 - 578
  • [40] Merkel Cell Carcinoma
    Wallis, S.
    Durham-hall, A.
    Tandon, N.
    Brotherston, T. M.
    Shrestha, B. M.
    [J]. JOURNAL OF NEPAL MEDICAL ASSOCIATION, 2010, 49 (02) : 151 - 154