Copper-catalyzed arylation of alkyl halides with arylaluminum reagents

被引：3

作者：

Shrestha, Bijay ^{[1
]}

Giri, Ramesh ^{[1
]}

机构：

[1] Univ New Mexico, Dept Chem & Chem Biol, Albuquerque, NM 87131 USA

来源：

BEILSTEIN JOURNAL OF ORGANIC CHEMISTRY | 2015年 / 11卷

关键词：

alkylation; arylalkanes; copper; cross-coupling; organoaluminum; CROSS-COUPLING REACTION; RECHARGEABLE MG BATTERIES; ARYL GRIGNARD-REAGENTS; SUZUKI-MIYAURA; ELECTROLYTE-SOLUTIONS; EFFICIENT SYNTHESIS; HETEROARYL IODIDES; DIRECT INSERTION; ORGANIC IODIDES; COMPLEXES;

D O I：

10.3762/bjoc.11.261

中图分类号：

O62 [有机化学];

学科分类号：

070303 ; 081704 ;

摘要：

We report a Cu-catalyzed coupling between triarylaluminum reagents and alkyl halides to form arylalkanes. The reaction proceeds in the presence of N,N,N',N'-tetramethyl-o-phenylenediamine (NN-1) as a ligand in combination with CuI as a catalyst. This catalyst system enables the coupling of primary alkyl iodides and bromides with electron-neutral and electron-rich triarylaluminum reagents and affords the cross-coupled products in good to excellent yields.

引用

页码：2400 / 2407

页数：8

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