Psoriasis and Obesity

被引：177

作者：

Jensen, Peter ^{[1
]}

Skov, Lone ^{[1
]}

机构：

[1] Herlev & Gentofte Hosp, Dept Dermatol & Allergy, Kildegardsvej 28, DK-2900 Hellerup, Denmark

来源：

DERMATOLOGY | 2016年 / 232卷 / 06期

关键词：

Obesity; Psoriasis; Nutritional care; BODY-MASS INDEX; ADIPONECTIN LEVELS; NECROSIS-FACTOR; LEPTIN LEVELS; WEIGHT-LOSS; TREATMENT MODALITIES; INSULIN SENSITIVITY; METABOLIC SYNDROME; CLINICAL-FEATURES; GASTRIC BYPASS;

D O I：

10.1159/000455840

中图分类号：

R75 [皮肤病学与性病学];

学科分类号：

100206 ;

摘要：

Psoriasis is a common chronic inflammatory skin disease with a complex pathogenesis consisting of a genetic component, immune dysfunction, and environmental factors. It is associated with numerous comorbidities including psoriatic arthritis, cardiovascular disease, metabolic syndrome, and obesity. Evidence suggests that obesity is a risk factor for incident psoriasis, aggravates existing psoriasis, and that weight reduction may improve the severity of psoriasis in overweight individuals. Excess body weight may interfere with the medical treatment used in psoriasis and adds to the cardiovascular risk profile in these patients, which underscores the importance of effective weight control regimens. In this review we examine the current literature with regard to the association between obesity and psoriasis. (C) 2017 S. Karger AG, Basel

引用

页码：633 / 639

页数：7

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